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Could leprosy reaction episodes be exacerbated by oral infections? / Episódios reacionais da hanseníase podem ser exacerbados por infecções orais?
Motta, Ana Carolina Fragoso; Furini, Renata Bazan; Simão, João Carlos Lopes; Vieira, Mariana Bellini; Ferreira, Maria Aparecida Nunes; Komesu, Marilena Chinali; Foss, Norma Tiraboschi.
  • Motta, Ana Carolina Fragoso; University of São Paulo. Ribeirão Preto Dental School. Department of Morphology, Stomatology and Physiology. Ribeirão Preto. BR
  • Furini, Renata Bazan; University of São Ribeirão Preto. Ribeirão Preto Medical School. Department of Internal Medicine. Division of Dermatology.
  • Simão, João Carlos Lopes; University of São Ribeirão Preto. Ribeirão Preto Medical School. Department of Internal Medicine. Division of Dermatology.
  • Vieira, Mariana Bellini; University of São Ribeirão Preto. Ribeirão Preto Medical School. Department of Internal Medicine. Division of Dermatology.
  • Ferreira, Maria Aparecida Nunes; University of São Ribeirão Preto. Ribeirão Preto Medical School. Department of Internal Medicine. Division of Dermatology.
  • Komesu, Marilena Chinali; University of São Paulo. Ribeirão Preto Dental School. Department of Morphology, Stomatology and Physiology. Ribeirão Preto. BR
  • Foss, Norma Tiraboschi; University of São Ribeirão Preto. Ribeirão Preto Medical School. Department of Internal Medicine. Division of Dermatology.
Rev. Soc. Bras. Med. Trop ; 44(5): 633-635, Sept.-Oct. 2011. ilus
Article in English | LILACS | ID: lil-602909
ABSTRACT

INTRODUCTION:

This study evaluated whether leprosy reactions could be associated with oral infection.

METHODS:

Leprosy patients (n = 38) with (Group I) and without (Group II) oral infections were selected. Reactions were identified from the clinical and histopathological features associated with serum C-reactive protein (CRP) and10kDa interferon-gamma-induced protein (IP-10) levels, determined before and after elimination of the foci of infection.

RESULTS:

Group I presented more reactions than group II did, and improvement of the reactions after dental treatment. Serum CRP and IP-10 did not differ before and after the dental treatment, but differed between the groups.

CONCLUSIONS:

Oral infection could be an exacerbating factor in leprosy reactions.
RESUMO

INTRODUÇÃO:

Este estudo avaliou se as reações hansênicas podem estar associadas a infecções orais.

MÉTODOS:

Pacientes com hanseníase (n=38) com (Grupo I) e sem (Grupo II) infecções orais foram selecionados. As reações foram identificadas pelas características clínicas, histopatológicas, associadas a proteína-C-reativa (PCR) e proteína indutora de interferon-gamma de 10kDa (IP-10) séricos determinados antes e após a eliminação dos focos de infecção.

RESULTADOS:

Grupo I apresentou mais reações que o grupo II, e melhora das reações após o tratamento odontológico. PCR e IP-10 séricos não diferiram antes e após o tratamento odontológico, entretanto diferiram entre os grupos.

CONCLUSÕES:

As infecções orais podem ser exacerbadores das reações hansênicas.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: C-Reactive Protein / Stomatognathic Diseases / Interferon-gamma / Leprosy Type of study: Observational study / Prognostic study / Risk factors Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2011 Type: Article / Project document Affiliation country: Brazil Institution/Affiliation country: University of São Paulo/BR

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Full text: Available Index: LILACS (Americas) Main subject: C-Reactive Protein / Stomatognathic Diseases / Interferon-gamma / Leprosy Type of study: Observational study / Prognostic study / Risk factors Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2011 Type: Article / Project document Affiliation country: Brazil Institution/Affiliation country: University of São Paulo/BR