Prenatal alcohol exposure did not affect impulsivity in rats that performed delay or probability discounting tasks
Psychol. neurosci. (Impr.)
;
4(1): 123-130, Jan.-June 2011. graf, tab
Article
in English
| LILACS
| ID: lil-604541
ABSTRACT
Individuals who fall under the spectrum of the Fetal Alcohol Syndrome have a higher prevalence of several cognitive disturbances, including a greater probability of being diagnosed with attention-deficit hyperactivity disorder (ADHD). Some of these effects, such as hyperactivity and attentional impairments, are already well established in the literature. The assessment of impulsive choice, however, has received little attention in human and animal studies. In the present study, we attempted to investigate the effects of prenatal ethanol exposure on two tasks related to impulsive choice that have never been studied in this condition delay and probability discounting. METHOD:
Rats prenatally exposed to ethanol (liquid diets with 0 percent, 10 percent, or 35 percent ethanol-derived calories [EDC] or laboratory chow) were trained to respond for food in either delay (n = 21) or probability (n = 48) discounting tasks performed in computer-controlled operant conditioning chambers.RESULTS:
Prenatal treatment failed to differentiate the rates at which the rats chose the larger reinforcer associated with delay - in a task in which 35 percent EDC was not tested - or risk, although the results suggest that further tests are warranted.
Full text:
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Index:
LILACS (Americas)
Main subject:
Cognition Disorders
/
Fetal Alcohol Spectrum Disorders
/
Impulsive Behavior
Type of study:
Risk factors
Limits:
Animals
Language:
English
Journal:
Psychol. neurosci. (Impr.)
Journal subject:
Neurology
/
Psychology
Year:
2011
Type:
Article
Affiliation country:
Brazil
/
United kingdom
Institution/Affiliation country:
King's College London/GB
/
Universidade Federal do Rio Grande do Sul/BR
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