Your browser doesn't support javascript.
loading
Prevalence of prediabetes in patients with metabolic risk / Prevalência de pré-diabetes em pacientes com risco metabólico
Matos, Lívia Nascimento de; Giorelli, Guilherme de Vieira; Saado, Amir; Dias, Cristiane Bitencourt.
  • Matos, Lívia Nascimento de; Hospital do Servidor Público Estadual de São Paulo - Francisco Morato de Oliveira. Institute for Medical Treatment. Department of Internal Medicine. BR
  • Giorelli, Guilherme de Vieira; Hospital do Servidor Público Estadual de São Paulo - Francisco Morato de Oliveira. Institute for Medical Treatment. Department of Internal Medicine. BR
  • Saado, Amir; Hospital do Servidor Público Estadual de São Paulo - Francisco Morato de Oliveira. Institute for Medical Treatment. Department of Internal Medicine. BR
  • Dias, Cristiane Bitencourt; Hospital do Servidor Público Estadual de São Paulo - Francisco Morato de Oliveira. Institute for Medical Treatment. Department of Internal Medicine. BR
São Paulo med. j ; 129(5): 300-308, 2011. ilus, tab
Article in English | LILACS | ID: lil-604789
ABSTRACT
CONTEXT AND

OBJECTIVE:

Early diagnosis of prediabetes should be done to avoid complications relating to diabetes mellitus (DM). The aim here was to assess the prevalence of prediabetes among individuals at high risk of developing DM, and to seek variables relating to glucose intolerance (GI) among individuals with normal fasting plasma glucose (FPG). DESIGN AND

SETTING:

Cross-sectional study at Hospital do Servidor Público Estadual, São Paulo.

METHODS:

The FPG and glucose tolerance test (GTT) were analyzed, from which the subjects were divided as follows group 1 (FPG and GTT both normal), group 2 (normal FPG but abnormal GTT), group 3 (abnormal FPG but normal GTT), and group 4 (FPG and GTT both abnormal). The subjects' clinical, laboratory and anthropometric profile was determined.

RESULTS:

138 subjects were studied 44 in group 1, 11 in group 2, 33 in group 3 and 50 in group 4. The prevalence of prediabetes was 68.0 percent. Group 4 individuals were older than group 1 individuals [69.0 (55.5-74.0) versus 58.9 ± 11.8 years; P < 0.05], with greater prevalence of risk conditions for DM [5.0 (4.0-5.0) versus 4.0 (3.0-5.0); P < 0.05]. Among individuals with normal FPG, GI prevalence was 20.0 percent. No variables analyzed correlated with GTT.

CONCLUSION:

The prevalence of prediabetes was 68.0 percent, and 20.0 percent of subjects with normal FPG had GI. Although some anthropometric, clinical and laboratory variables have been correlated with DM and prediabetes, none, except for GTT, was able to screen for GI among subjects with normal FPG in the present study.
RESUMO
CONTEXTO E

OBJETIVO:

Deve-se diagnosticar o estado pré-diabético precocemente para evitar as complicações do diabetes mellitus (DM). Objetiva-se avaliar a prevalência de estado pré-diabético entre indivíduos sob risco de desenvolvimento de DM, buscando variáveis relacionadas à intolerância à glicose (IG) naqueles com glicemia de jejum (GJ) normal. TIPO DE ESTUDO E LOCAL Estudo transversal no Hospital do Servidor Público Estadual, São Paulo.

MÉTODOS:

Analisou-se GJ e teste oral de tolerância a glicose (GTT), que determinaram a seguinte divisão grupo 1 (GJ e GTT normais), grupo 2 (GJ normal e GTT alterado), grupo 3 (GJ alterada e GTT normal) e grupo 4 (GJ e GTT alterados). Determinou-se o perfil clínico, laboratorial e antropométrico dos indivíduos estudados.

RESULTADOS:

Estudaram-se 138 indivíduos 44 no grupo 1, 11 no grupo 2, 33 no grupo 3 e 50 no grupo 4. A prevalência de estado pré-diabético foi 68,0 por cento. Indivíduos do grupo 4, em relação ao grupo 1, demonstraram idade mais avançada [69,0 (55,5-74,0) versus 58,9 ± 11,8 anos, P < 0,05] e maior prevalência de condições de risco para o DM [5,0 (4,0-5,0) versus 4,0 (3,0-5,0), P < 0,05]. Dentre aqueles com GJ normal, 20,0 por cento apresentaram IG. Nenhuma variável se correlacionou com o GTT.

CONCLUSÃO:

A prevalência de estado pré-diabético foi 68,0 por cento; 20,0 por cento daqueles com GJ normal apresentaram IG. Apesar de algumas variáveis clínicas, antropométricas e laboratoriais estarem descritas como relacionadas ao DM e ao estado pré-diabético, no presente estudo, nenhuma, à exceção do GTT, foi capaz de rastrear a presença de IG entre aqueles com GJ normal.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Prediabetic State / Blood Glucose / Glucose Intolerance Type of study: Etiology study / Observational study / Prevalence study / Prognostic study / Risk factors / Screening study Limits: Aged / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: São Paulo med. j Journal subject: Cirurgia Geral / Ciˆncia / Ginecologia / Medicine / Medicina Interna / Obstetr¡cia / Pediatria / Sa£de Mental / Sa£de P£blica Year: 2011 Type: Article Affiliation country: Brazil Institution/Affiliation country: Hospital do Servidor Público Estadual de São Paulo - Francisco Morato de Oliveira/BR

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Index: LILACS (Americas) Main subject: Prediabetic State / Blood Glucose / Glucose Intolerance Type of study: Etiology study / Observational study / Prevalence study / Prognostic study / Risk factors / Screening study Limits: Aged / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: São Paulo med. j Journal subject: Cirurgia Geral / Ciˆncia / Ginecologia / Medicine / Medicina Interna / Obstetr¡cia / Pediatria / Sa£de Mental / Sa£de P£blica Year: 2011 Type: Article Affiliation country: Brazil Institution/Affiliation country: Hospital do Servidor Público Estadual de São Paulo - Francisco Morato de Oliveira/BR