Acute bromopride treatments: effects on general activity and inhibitory avoidance in rats
Braz. j. med. biol. res
; 21(4): 841-3, 1988. ilus, tab
Article
in En
| LILACS
| ID: lil-60804
Responsible library:
BR26.1
ABSTRACT
Bromopride (BRO), a dopamine D2 blocker used in gastroenterology clinics, was tested acutely in rats for effects on general activity, measured in an open-field test, and on inhibitory avoidance behavior. Rats that received 2.5 and 5.0 mg/Kg BRO showed lower locomotion and rearing frequencies than controls, and 5.0 mg/Kg BRO blocked the inhibitory avoidance response. The data suggest that BRO may have neuroleptic effects
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Index:
LILACS
Main subject:
Avoidance Learning
/
Locomotion
/
Metoclopramide
Limits:
Animals
Language:
En
Journal:
Braz. j. med. biol. res
Journal subject:
BIOLOGIA
/
MEDICINA
Year:
1988
Type:
Article
/
Congress and conference