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Evaluación de predictores clínicos de bacteriemia en adultos hospitalizados por neumonía adquirida en la comunidad / Evaluation of clinical predictors of bacteremia in adults hospitalized for community-acquired pneumonia
Díaz Parodi, Germán Ignacio; Musacchio, Héctor Mario.
  • Díaz Parodi, Germán Ignacio; Hospital J. B. Iturraspe. Servicio de Clínica Médica. Santa Fe. AR
  • Musacchio, Héctor Mario; Hospital J. B. Iturraspe. Servicio de Clínica Médica. Santa Fe. AR
Rev. panam. salud pública ; 29(6): 393-398, June 2011. tab
Article in Spanish | LILACS | ID: lil-608268
RESUMEN

OBJETIVO:

Identificar elementos clínicos sencillos que hagan posible determinar adecuadamente los casos con mayor probabilidad de presentar aislamientos bacterianos en los hemocultivos.

MÉTODOS:

Estudio de casos y controles con pacientes internados por neumonía adquirida en la comunidad entre 1998 y 2009, definiéndose como casos a los pacientes que presentaron hemocultivos positivos y como controles a aquellos con hemocultivos negativos. Se registraron variables demográficas y clínicas y se las sometió a un análisis bivariado. Las que presentaron diferencias estadísticamente significativas entre los grupos fueron introducidas en un modelo de regresión logística para definir predictores independientes y generar un modelo de predicción clínica.

RESULTADOS:

De los 322 pacientes estudiados, 15,2 por ciento tuvo hemocultivos positivos. Diez variables mostraron diferencias significativas, pero solo tres (temperatura <38°C, sodio <135 mEq/L y puntaje CURB-65) fueron seleccionadas para el análisis multivariado. El modelo desarrollado mostró escasa capacidad para predecir el resultado de los hemocultivos (R² = 0,176; Hosmer-Lemeshow P = 0,338).

CONCLUSIONES:

Los datos obtenidos en esta serie no evidenciaron elementos clínicos con capacidad suficiente para predecir el resultado de los hemocultivos.
ABSTRACT

OBJECTIVE:

Identify simple clinical elements that can be used to adequately determine the cases with the highest probability of presenting bacterial isolates in blood cultures.

METHODS:

Case-control study with patients hospitalized for community-acquired pneumonia from 1998-2009. Patients with positive blood cultures were defined as cases, and patients with negative blood cultures were defined as controls. The demographic and clinical variables were recorded and a bivariate analysis was conducted. The variables with statistically significant differences between the groups were introduced in a logistic regression model in order to define the independent predictors and generate a clinical prediction model.

RESULTS:

A total of 15.2 percent of the 322 patients studied had positive blood cultures. Ten variables showed significant differences, but only three variables (temperature <38°C, sodium <135 mEq/L and CURB-65 score) were selected for the multivariate analysis. The model developed showed limited capacity to predict the result of the blood cultures (R² = 0.176; Hosmer-Lemeshow P = 0.338).

CONCLUSIONS:

The data obtained in this series did not demonstrate clinical elements with sufficient capacity to predict the result of the blood cultures.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Bacteremia / Community-Acquired Infections / Pneumonia, Bacterial / Inpatients Type of study: Etiology study / Observational study / Prognostic study / Risk factors Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male Country/Region as subject: South America / Argentina Language: Spanish Journal: Rev. panam. salud pública Journal subject: Public Health Year: 2011 Type: Article Affiliation country: Argentina Institution/Affiliation country: Hospital J. B. Iturraspe/AR

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Full text: Available Index: LILACS (Americas) Main subject: Bacteremia / Community-Acquired Infections / Pneumonia, Bacterial / Inpatients Type of study: Etiology study / Observational study / Prognostic study / Risk factors Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male Country/Region as subject: South America / Argentina Language: Spanish Journal: Rev. panam. salud pública Journal subject: Public Health Year: 2011 Type: Article Affiliation country: Argentina Institution/Affiliation country: Hospital J. B. Iturraspe/AR