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Avances en el diagnóstico de las alteraciones del eje somatotrófico que causan retardo del crecimiento / An update on the diagnosis of growth hormone axis disturbances that cause stunting
Hernández C., M. Isabel; Cassorla G., Fernando.
  • Hernández C., M. Isabel; Universidad de Chile. Facultad de Medicina. Instituto de Investigaciones Materno Infantil. CL
  • Cassorla G., Fernando; Universidad de Chile. Facultad de Medicina. Instituto de Investigaciones Materno Infantil. CL
Rev. chil. endocrinol. diabetes ; 2(3): 173-178, jul. 2009. ilus, tab
Article in Spanish | LILACS | ID: lil-610296
ABSTRACT
Human growth is a complex process regulated by several genes, most of which are unknown. Recently, our knowledge regarding the etiology of genetically determined causes of short stature has greatly increased, so molecular analysis is becoming essential for the diagnosis of growth retardation. The advances in our understanding of the molecular mechanisms involved in the function of the somatotrophic axis have resulted in a dramatic enhancement of our ability to diagnose and treat growth disorders. We hope that in the next few years improved methods for identifying specific abnormalities which cause short stature will expand our ability to diagnose other causes of growth retardation, and reduce the proportion of patients with "idiopathic" short stature.
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Index: LILACS (Americas) Main subject: Body Height / Growth Hormone / Growth Disorders Type of study: Diagnostic study / Prognostic study Limits: Humans Language: Spanish Journal: Rev. chil. endocrinol. diabetes Journal subject: Endocrinology Year: 2009 Type: Article Affiliation country: Chile Institution/Affiliation country: Universidad de Chile/CL

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Index: LILACS (Americas) Main subject: Body Height / Growth Hormone / Growth Disorders Type of study: Diagnostic study / Prognostic study Limits: Humans Language: Spanish Journal: Rev. chil. endocrinol. diabetes Journal subject: Endocrinology Year: 2009 Type: Article Affiliation country: Chile Institution/Affiliation country: Universidad de Chile/CL