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Factors influencing possible delay in the diagnosis of Alzheimer's disease: Findings from a tertiary Public University Hospital / Fatores que influenciam o possível atraso no diagnóstico da doença de Alzheimer: achados de um Hospital Universitário Público
Miranda, Luís Felipe José Ravic de; Matoso, Rafael de Oliveira; Rodrigues, Márlon Vieira; Lima, Thiago Oliveira Lemos de; Nascimento, Adriano Fiorini; Carvalho, Fernando Castro; Melo Moreira, Débora Regina de; Fernandes, Jeferson Cruz; Paula, Jonas Jardim de; Magno, Luiz Alexandre V; Caramelli, Paulo; Moraes, Edgar Nunes de.
  • Miranda, Luís Felipe José Ravic de; Federal University of Minas Gerais. Department of Clinical Medicine. Belo Horizonte, MG. BR
  • Matoso, Rafael de Oliveira; Federal University of Minas Gerais. Department of Clinical Medicine. Belo Horizonte, MG. BR
  • Rodrigues, Márlon Vieira; Federal University of Minas Gerais. Department of Clinical Medicine. Belo Horizonte, MG. BR
  • Lima, Thiago Oliveira Lemos de; Federal University of Minas Gerais. Department of Clinical Medicine. Belo Horizonte, MG. BR
  • Nascimento, Adriano Fiorini; Federal University of Minas Gerais. Department of Clinical Medicine. Belo Horizonte, MG. BR
  • Carvalho, Fernando Castro; Federal University of Minas Gerais. Department of Clinical Medicine. Belo Horizonte, MG. BR
  • Melo Moreira, Débora Regina de; Federal University of Minas Gerais. Department of Clinical Medicine. Belo Horizonte, MG. BR
  • Fernandes, Jeferson Cruz; Federal University of Minas Gerais. School of Psychology. Belo Horizonte, MG. BR
  • Paula, Jonas Jardim de; Federal University of Minas Gerais. Research Laboratory of Neuropsychology. Belo Horizonte, MG. BR
  • Magno, Luiz Alexandre V; Federal University of Minas Gerais. INCT of Molecular Medicine. Molecular Medicine - Neuroscience Laboratory. Belo Horizonte, MG. BR
  • Caramelli, Paulo; Federal University of Minas Gerais. Department of Clinical Medicine. Belo Horizonte, MG. BR
  • Moraes, Edgar Nunes de; Federal University of Minas Gerais. Department of Clinical Medicine. Belo Horizonte, MG. BR
Dement. neuropsychol ; 5(4): 328-331, dez. 2011. tab
Article in English | LILACS | ID: lil-612063
ABSTRACT
Alzheimer's disease (AD) is characterized by impairment in memory and autonomy, causing excessive pressure on family and an overburdened health care system. Early diagnosis, with the appropriate treatment, is important to reduce the pattern of disease progression. Objective: The study sought to identify the most probable causes of delay in diagnosis. Methods: A cross-sectional study involving AD patients followed at an Outpatient Geriatric Clinic from a tertiary public university hospital was conducted between June 2009 and February 2011. Results: Ninety-four patients were evaluated (66% women), aged 77.76±6.8 years and with median educational level of 3 years (95% CI 2.7-3.80). Regarding severity of dementia, 51.8% of patients were classified as having mild dementia (CDR 1), 40% moderate dementia (CDR 2) and 8.2% severe dementia (CDR 3). Mean educational level of caregivers was 8.3±3.9 years. Among those who believed there was a delay, 36% stated that the "family thought that the changes were normal for the age of the patient" reporting average delay of 1.8 years (95% CI: 1.3-2.5) while 45.3% stated that the "doctor did not reach a diagnosis" reporting a median delay of 1.5 years (95% CI: 1.4-2.3). Conclusion: Based on these results, it can be concluded the time between onset of symptoms and diagnosis was excessive. This study may be useful to help increase awareness of issues not sufficiently discussed in the literature, such as diagnostic delay and influence of caregivers' educational level on treatment.
RESUMO
A doença de Alzheimer é caracterizada por comprometimento na memória e na autonomia, causando pressão excessiva em familiares e sobrecarregando o sistema público de saúde. O diagnóstico precoce, com o tratamento adequado, é importante para reduzir o padrão de evolução da doença. Objetivo: O estudo pretende identificar as causas mais prováveis de atraso no diagnóstico. Métodos: Trata-se de um estudo transversal envolvendo pacientes com DA acompanhados em Ambulatório de Geriatria de um hospital terciário público entre junho de 2009 e fevereiro de 2011. Resultados: Noventa e quatro pacientes foram avaliados (66% mulheres), com média de idade de 77,8±6,8 anos e com mediana de escolaridade de 3 anos (IC 95%: 2,7-3,8). Quanto à gravidade da doença, 51,8% foram classificados como demência leve (CDR 1), 40% como demência moderada (CDR 2) e 8,2% como demência grave (CDR 3). A escolaridade do cuidador foi de 8,3±3,9 anos. Entre aqueles que acreditavam que havia um atraso no diagnóstico, 36% responderam que "a família achava as alterações como normais para a idade do paciente", com média de 1,8 anos (IC 95%: 1,3-2,5) e 45,3% responderam que "o médico não fez o diagnóstico", com mediana de 1,5 anos (IC 95%: 1,4-2,3). Foi observado que o tempo entre o início dos sintomas e o diagnóstico foi maior do que deveria ser. Conclusão: Este estudo pode contribuir para aumentar o conhecimento sobre questões ainda pouco discutidas na literatura científica, como atraso no diagnóstico e influência da escolaridade do cuidador no tratamento.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Caregivers / Educational Status / Delayed Diagnosis / Alzheimer Disease Type of study: Diagnostic study / Observational study / Prevalence study / Prognostic study / Screening study Limits: Humans Language: English Journal: Dement. neuropsychol Journal subject: NEUROCIENCIAS / Neurology / Psychology / Psychiatry Year: 2011 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Minas Gerais/BR

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Full text: Available Index: LILACS (Americas) Main subject: Caregivers / Educational Status / Delayed Diagnosis / Alzheimer Disease Type of study: Diagnostic study / Observational study / Prevalence study / Prognostic study / Screening study Limits: Humans Language: English Journal: Dement. neuropsychol Journal subject: NEUROCIENCIAS / Neurology / Psychology / Psychiatry Year: 2011 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Minas Gerais/BR