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Resultados actuales de la pancreatoduodenectomía para el tratamiento de los tumores periampulares y análisis de factores pronósticos de sobrevida / Results of pancreaticoduodenectomy in the treatment of periampullary tumors
Norero, Enrique; Viñuela, Eduardo; Báez, Sergio; Martínez, Cristian; Reyes, Julio; Kusanovic, Rodrigo; Sanhueza, Marcel; Aguayo, Gloria; Calvo, Alfonso; Mege, Rose Marie; Caracci, Mario; Díaz, Alfonso.
  • Norero, Enrique; Hospital Sótero del Río. Servicio de Salud Metropolitano Sur Oriente. Servicio de Cirugía. Cirugía Digestiva. CL
  • Viñuela, Eduardo; Hospital Sótero del Río. Servicio de Salud Metropolitano Sur Oriente. Servicio de Cirugía. Cirugía Digestiva. CL
  • Báez, Sergio; Hospital Sótero del Río. Servicio de Salud Metropolitano Sur Oriente. Servicio de Cirugía. Cirugía Digestiva. CL
  • Martínez, Cristian; Hospital Sótero del Río. Servicio de Salud Metropolitano Sur Oriente. Servicio de Cirugía. Cirugía Digestiva. CL
  • Reyes, Julio; Hospital Sótero del Río. Servicio de Salud Metropolitano Sur Oriente. Servicio de Cirugía. Cirugía Digestiva. CL
  • Kusanovic, Rodrigo; Hospital Sótero del Río. Servicio de Salud Metropolitano Sur Oriente. Servicio de Cirugía. Cirugía Digestiva. CL
  • Sanhueza, Marcel; Hospital Sótero del Río. Servicio de Salud Metropolitano Sur Oriente. Servicio de Cirugía. Cirugía Digestiva. CL
  • Aguayo, Gloria; Hospital Sótero del Río. Servicio de Salud Metropolitano Sur Oriente. Servicio de Anatomía Patológica. CL
  • Calvo, Alfonso; Hospital Sótero del Río. Servicio de Salud Metropolitano Sur Oriente. Servicio de Cirugía. Cirugía Digestiva. CL
  • Mege, Rose Marie; Hospital Sótero del Río. Servicio de Salud Metropolitano Sur Oriente. Servicio de Cirugía. Cirugía Digestiva. CL
  • Caracci, Mario; Hospital Sótero del Río. Servicio de Salud Metropolitano Sur Oriente. Servicio de Cirugía. Cirugía Digestiva. CL
  • Díaz, Alfonso; Hospital Sótero del Río. Servicio de Salud Metropolitano Sur Oriente. Servicio de Cirugía. Cirugía Digestiva. CL
Rev. méd. Chile ; 139(8): 1015-1024, ago. 2011. ilus
Article in Spanish | LILACS | ID: lil-612216
ABSTRACT

Background:

The diagnosis and treatment of periampullary tumors represents a challenge for current medicine.

Aim:

To review the results of pancreaticoduodenectomy (PDD) in the treatment of periampullary tumors and to identify risk factors that impact the long-term survival. Patients and

Methods:

We performed a retrospective study of patients who underwent a PDD for periampullary tumors between 1993 and 2009. We reviewed perioperative results and long term survival. We performed a multivariate analysis for long-term survival.

Results:

A PDD was performed in 181 patients aged 58 ± 12 years (98 females). Piloric preservation was done in 53 percent and a pancreatogastric anastomosis was used in 94 percent of cases. Morbidity was 62 percent and postoperative mortality was 5.5 percent. Pancreatic cancer was the most frequent pathological finding in 41 percent, followed by ampullary cancer in 28 percent and distal bile duct cancer in 16 percent. Median survival was 17 months, with a five years survival of 24 percent. Survival for ampullary tumors was 28 months with a five years survival of 32 percent. The median and five years survival were 14 months and 16 percent for bile duct cancer and 11 months and 14 percent for pancreatic cancer. Multivariate analysis identified tumor type (pancreas /bile duct) and lymph node dissemination as independent predictors of mortality.

Conclusions:

One quarter of patients experienced long term survival. Mortality predictors were tumor type and lymph node dissemination.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Pancreatic Neoplasms / Ampulla of Vater / Pancreaticoduodenectomy / Common Bile Duct Neoplasms / Carcinoma, Pancreatic Ductal Type of study: Observational study / Prognostic study / Risk factors Limits: Female / Humans / Male Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2011 Type: Article Affiliation country: Chile Institution/Affiliation country: Hospital Sótero del Río/CL

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Full text: Available Index: LILACS (Americas) Main subject: Pancreatic Neoplasms / Ampulla of Vater / Pancreaticoduodenectomy / Common Bile Duct Neoplasms / Carcinoma, Pancreatic Ductal Type of study: Observational study / Prognostic study / Risk factors Limits: Female / Humans / Male Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2011 Type: Article Affiliation country: Chile Institution/Affiliation country: Hospital Sótero del Río/CL