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Central nervous system lymphoma: magnetic resonance imaging features at presentation / Linfoma do sistema nervoso central: características da imagem de ressonância magnética à apresentação
Schwingel, Ricardo; Reis, Fabiano; Zanardi, Veronica A; Queiroz, Luciano S; França Júnior, Marcondes C.
  • Schwingel, Ricardo; State University of Campinas. School of Medical Sciences. São Paulo. BR
  • Reis, Fabiano; State University of Campinas. School of Medical Sciences. Department of Radiology. São Paulo. BR
  • Zanardi, Veronica A; State University of Campinas. School of Medical Sciences. Department of Radiology. São Paulo. BR
  • Queiroz, Luciano S; State University of Campinas. School of Medical Sciences. Department of Pathology. São Paulo. BR
  • França Júnior, Marcondes C; State University of Campinas. School of Medical Sciences. Department of Neurology. São Paulo. BR
Arq. neuropsiquiatr ; 70(2): 97-101, Feb. 2012. ilus, tab
Article in English | LILACS | ID: lil-612688
ABSTRACT

OBJECTIVE:

This paper aimed at studying presentations of the central nervous system (CNS) lymphoma using structural images obtained by magnetic resonance imaging (MRI).

METHODS:

The MRI features at presentation of 15 patients diagnosed with CNS lymphoma in a university hospital, between January 1999 and March 2011, were analyzed by frequency and cross tabulation.

RESULTS:

All patients had supratentorial lesions; and four had infra- and supratentorial lesions. The signal intensity on T1 and T2 weighted images was predominantly hypo- or isointense. In the T2 weighted images, single lesions were associated with a hypointense signal component. Six patients presented necrosis, all of them showed perilesional abnormal white matter, nine had meningeal involvement, and five had subependymal spread. Subependymal spread and meningeal involvement tended to occur in younger patients.

CONCLUSION:

Presentations of lymphoma are very pleomorphic, but some of them should point to this diagnostic possibility.
RESUMO

OBJETIVO:

Este trabalho teve como objetivo estudar as apresentações do linfoma do sistema nervoso central (SNC) por meio de imagens estruturais, obtidas por ressonância magnética (RM).

MÉTODOS:

Foram analisadas as características das imagens por RM, à apresentação, de 15 pacientes diagnosticados com linfoma do SNC em um hospital universitário, entre janeiro de 1999 e março de 2011, pela frequência e por tabulação cruzada.

RESULTADOS:

Todos os pacientes apresentaram lesões supratentoriais; em quatro (27 por cento) havia lesões infra e supratentoriais. A intensidade do sinal em T1 e T2 foi predominantemente hipo ou isointensa. Lesões únicas foram associadas ao componente de sinal hipointenso nas imagens ponderadas em T2. Seis pacientes apresentaram necrose. Foram encontrados alteração de sinal da substância branca perilesional em todos os pacientes, acometimento meníngeo em nove e disseminação subependimária em cinco. Disseminação subependimária e acometimento meníngeo tenderam a ocorrer nos pacientes mais jovens.

CONCLUSÃO:

As apresentações do linfoma no SNC são pleomórficas, mas algumas delas podem apontar para essa possibilidade diagnóstica.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Magnetic Resonance Imaging / Central Nervous System Neoplasms / Lymphoma Limits: Adult / Aged / Female / Humans / Male Language: English Journal: Arq. neuropsiquiatr Journal subject: Neurology / Psychiatry Year: 2012 Type: Article / Project document Affiliation country: Brazil Institution/Affiliation country: State University of Campinas/BR

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Full text: Available Index: LILACS (Americas) Main subject: Magnetic Resonance Imaging / Central Nervous System Neoplasms / Lymphoma Limits: Adult / Aged / Female / Humans / Male Language: English Journal: Arq. neuropsiquiatr Journal subject: Neurology / Psychiatry Year: 2012 Type: Article / Project document Affiliation country: Brazil Institution/Affiliation country: State University of Campinas/BR