First detection of Rio Negro virus (Venezuelan equine encephalitis complex subtype VI) in Córdoba, Argentina
Mem. Inst. Oswaldo Cruz
;
107(1): 125-128, Feb. 2012. mapas, tab
Article
in English
| LILACS
| ID: lil-612815
ABSTRACT
Rio Negro virus (RNV) (Venezuelan equine encephalitis subtype VI) circulates only in Argentina; in northern provinces, isolates have been obtained from mosquitoes and rodents since 1980 and have been associated with acute febrile illness in humans. However, no studies of RNV have been performed in the central area of the country. We carried out molecular and serological detection of RNV in Córdoba, a province of the central part of the country, in mosquitoes and humans, respectively. One mosquito pool tested positive for alphavirus RNA by reverse transcriptase-nested polymerase chain reaction (RT-nested PCR). Subsequent sequencing determined that this alphavirus grouped with RNV. Serological studies detected antibodies to RNV in one human serum sample, which was obtained during the same period that RNV was detected using the aforementioned molecular methods. This is the first report of RNV circulation in the central area of Argentina, indicating an expansion of its original distribution. These results highlight the importance of strengthening surveillance procedures in endemic areas, as well as in new regions where RNV may emerge.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Encephalitis Virus, Venezuelan Equine
/
Encephalomyelitis, Venezuelan Equine
/
Insect Vectors
/
Culicidae
Type of study:
Diagnostic study
Limits:
Aged80
/
Animals
/
Humans
Country/Region as subject:
South America
/
Argentina
/
Venezuela
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2012
Type:
Article
Affiliation country:
Argentina
Institution/Affiliation country:
Universidad Nacional de Córdoba/AR
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