Comparative evaluation under routine conditions of the nitrate reduction assay, the proportion assay and the MGIT 960 assay for drug susceptibility testing of clinical isolates of Mycobacterium tuberculosis
Mem. Inst. Oswaldo Cruz
;
107(1): 142-144, Feb. 2012. tab
Article
in English
| LILACS
| ID: lil-612819
ABSTRACT
The performance of the nitrate reductase assay (NRA) was compared with the proportion method (PM) on Lowenstein-Jensen medium and the BACTEC MGIT960 assay under routine conditions using 160 clinical isolates of Mycobacterium tuberculosis with a high proportion of resistant strains. The mean time to obtain results was 8.8 days and the overall agreements between NRA and PM and NRA and M960 were 95 percent and 94 percent, respectively. NRA was easy to perform and represents a useful tool for the rapid screening of drug-resistant M. tuberculosis strains in low-resource countries.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Microbial Sensitivity Tests
/
Culture Media
/
Nitrate Reductase
/
Mycobacterium tuberculosis
/
Antitubercular Agents
Type of study:
Evaluation studies
Limits:
Humans
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2012
Type:
Article
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