Vulvovaginal candidiasis in Mato Grosso, Brazil: pregnancy status, causative species and drugs tests
Braz. j. microbiol
;
42(4): 1300-1307, Oct.-Dec. 2011. tab
Article
in English
| LILACS
| ID: lil-614588
ABSTRACT
Causative agent in majority of VVC is Candida albicans, but infection due to non-C. albicans is common. Use of empiric antifungal therapy in Brazil due to syndromic management of vulvovaginitis could act as risk factor for increase resistance among VVC causative agents. From Mato Grosso patients, 160 with culture-proved among 404 women who had clinical symptoms of VVC, were enrolled in this study. 70 non-pregnant women and 90 pregnant women were included. Candida albicans was the most prevalent, representing 72.9 percent in the non-pregnant group and 92.3 percent in the pregnant group. Differences in species distribution were noted between the two groups, being C. parapsilosis the second more prevalent species among non-pregnant women. Susceptibility testing revealed high susceptibility to fluconazole (except for C. krusei), itraconazole, ketoconazole, and amphotericin B regardless the species (C. albicans, C. parapsilosis, C. tropicalis, C. glabrata, C. krusei) analyzed.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Vulvovaginitis
/
Candida albicans
/
Candidiasis, Vulvovaginal
/
Drug Resistance, Microbial
/
Diagnostic Techniques and Procedures
/
Disease Susceptibility
/
Antifungal Agents
Type of study:
Diagnostic study
/
Prevalence study
/
Risk factors
Limits:
Female
/
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Braz. j. microbiol
Journal subject:
Microbiology
Year:
2011
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal de Mato Grosso/BR
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