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Comportamiento clínico-terapéutico de Fasciola hepatica en una serie de 87 pacientes / Clinical and therapeutic behaviour of Fasciola hepatica in a series of 87 patients
Díaz Fernández, René; Garcés Martínez, Madelyn; Millán Álvarez, Leslie M; Pérez Lastre, Jorge; Millán Marcelo, Juan Carlos.
  • Díaz Fernández, René; Instituto de Medicina Tropical Pedo Kourí. La Habana. CU
  • Garcés Martínez, Madelyn; Instituto de Medicina Tropical Pedo Kourí. La Habana. CU
  • Millán Álvarez, Leslie M; Instituto de Medicina Tropical Pedo Kourí. La Habana. CU
  • Pérez Lastre, Jorge; Instituto de Medicina Tropical Pedo Kourí. La Habana. CU
  • Millán Marcelo, Juan Carlos; Instituto de Medicina Tropical Pedo Kourí. La Habana. CU
Rev. cuba. med. trop ; 63(3): 268-274, sep.-dic. 2011.
Article in Spanish | LILACS | ID: lil-615572
RESUMEN

Introducción:

la fasciolosis, por Fasciola hepatica, muestra a escala mundial un incremento en la incidencia de enfermos en los últimos años. Cuba se encuentra entre aquellos países donde se reportan casos esporádicos y algunos brotes epidémicos.

Objetivo:

describir el comportamiento clínico-terapéutico de esta trematodiosis de trasmisión digestiva en una serie de 87 pacientes ingresados en el Instituto de Medicina Tropical "Pedro Kourí" desde enero de 1996 a diciembre de 2005.

Método:

los pacientes se dividieron en 2 grupos atendiendo al fármaco prescrito, dihidroemetina o triclabendazol. Se recogieron las variables clínicas al inicio del diagnóstico y 90 d después del tratamiento; se hallaron las medias y la desviación estándar.

Resultados:

el sexo masculino predominó discretamente con 54 por ciento en nuestra serie de pacientes ingresados en el servicio de medicina tropical del instituto. La ingestión de berro (Nasturtium officinale) estuvo presente en casi la mitad de los pacientes. El dolor abdominal, fiebre y astenia resultaron los síntomas de mayor frecuencia. El triclabendazol y la dihidroemetina fueron útiles en el tratamiento.

Conclusiones:

se comprobó la utilidad de los exámenes de laboratorio en el diagnóstico y seguimiento de los enfermos. Los antiparasitarios dihidroemetina y triclabendazol resultaron efectivos a las dosis utilizadas con efectos adversos menores.
ABSTRACT

Introduction:

in the last few years, the Incidence rate of fascioliosis caused by Fasciola hepatica has increased worldwide. Cuba is one of the countries that have reported sporadic cases and also some outbreaks of fasciolosis.

Objective:

to describe clinical and therapeutic features of this trematodiasis of digestive transmission found in 87 patients, who had been admitted to "Pedro Kourí" Institute of Tropical Medicine from January 1996 to December 2005.

Methods:

patients were divided into 2 groups according to the prescribed drug, that is, triclabendazole and dihydroemetine. The clinical variables were collected at the time of diagnosis and 90 days after treatment; the means and the standard deviation were estimated.

Results:

males was slightly predominant (54) in our series of patients admitted to the institute service. Consumption of watercress (Nasturtium officinale) was found in almost half of the patients. Abdominal pain, fever and malaise were the most frequent symptoms. Both drugs were useful to treat F. hepatica.

Conclusions:

this study showed the usefulness of lab tests for diagnosis and follow-up of patients after treatment. The anti-parasitic drugs dihydroemetine and triclabendazole proved to be effective at the prescribed doses in this research with minor adverse effects.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Benzimidazoles / Emetine / Fascioliasis / Anthelmintics Limits: Animals / Female / Humans / Male Language: Spanish Journal: Rev. cuba. med. trop Journal subject: Tropical Medicine Year: 2011 Type: Article Affiliation country: Cuba Institution/Affiliation country: Instituto de Medicina Tropical Pedo Kourí/CU

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Full text: Available Index: LILACS (Americas) Main subject: Benzimidazoles / Emetine / Fascioliasis / Anthelmintics Limits: Animals / Female / Humans / Male Language: Spanish Journal: Rev. cuba. med. trop Journal subject: Tropical Medicine Year: 2011 Type: Article Affiliation country: Cuba Institution/Affiliation country: Instituto de Medicina Tropical Pedo Kourí/CU