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Genotoxicity of plant extracts
Vargas, Vera M. F; Guidobono, Régis R; Henriques, João A. P.
  • Vargas, Vera M. F; Secretaria da Saúde do Meio Ambiente. Departamento do Meio Ambiente. Porto Alegre. BR
  • Guidobono, Régis R; Secretaria da Saúde do Meio Ambiente. Departamento do Meio Ambiente. Porto Alegre. BR
  • Henriques, João A. P; UFRGS. Instituto de Biociências. Departamento de Fisiologia. Porto Alegre. BR
Mem. Inst. Oswaldo Cruz ; 86(supl.2): 67-70, 1991. tab
Article in English | LILACS | ID: lil-623943
ABSTRACT
Aqueous extracts of seven species used in Brazilian popular medicine (Achyrocline satureoides, Iodina rhombifolia, Desmodium incanum, Baccharis anomala, Tibouchina asperior, Luehea divaricata, Maytenus ilicifolia) were screened to the presence of mutagenic activity in the Ames test (Salmonella/microsome). Positive results were obtained for A. satureoides, B anomala and L. divaricata with microsomal activation. As shown elsewhere (Vargas et al., 1990) the metabolites of A. satureoides extract also show the capacity to induce prophage and/or SOS response in microscreen phage induction assay and SOS spot chromotest.
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Full text: Available Index: LILACS (Americas) Main subject: Salmonella typhimurium / Virus Activation / SOS Response, Genetics / Microsomes, Liver / Plant Extracts / Mutagens Limits: Animals Country/Region as subject: South America / Brazil Language: English Journal: Mem. Inst. Oswaldo Cruz Journal subject: Tropical Medicine / Parasitology Year: 1991 Type: Article / Congress and conference Affiliation country: Brazil Institution/Affiliation country: Secretaria da Saúde do Meio Ambiente/BR / UFRGS/BR

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Full text: Available Index: LILACS (Americas) Main subject: Salmonella typhimurium / Virus Activation / SOS Response, Genetics / Microsomes, Liver / Plant Extracts / Mutagens Limits: Animals Country/Region as subject: South America / Brazil Language: English Journal: Mem. Inst. Oswaldo Cruz Journal subject: Tropical Medicine / Parasitology Year: 1991 Type: Article / Congress and conference Affiliation country: Brazil Institution/Affiliation country: Secretaria da Saúde do Meio Ambiente/BR / UFRGS/BR