Toxicological and toxicogenetic effects of plants used in popular medicine and in cattle food
Mem. Inst. Oswaldo Cruz
;
86(supl.2): 89-91, 1991. tab
Article
in English
| LILACS
| ID: lil-623948
ABSTRACT
Toxicological and toxicogenetic effects of aqueous (tea) and hexanica fruit extract of Indigofera suffruticosa Mill, and hydroalcoholic root extract od Solanum agrarium Stendt. Were evaluated in Balb C male mice intraperitoneally exposed. A hepatotoxic effect was observed just for animals treated with aqueous fruit extract of I. suffruticosa. In relation to the toxicogenetic effect, just the group trreated with 12.5% of toxic dose of aqueous fruit extract of I. suffruticosa showed a statistically significant increase in the frequency of cells with chromosome aberrations (cytogenetic effect), although a slight increase was also observed for the highest dose (25% of LF50_ of hydroalcoholic root extract of S. agrarium. The results obtanied show that before S. agrarium is used as medicine and before the wide use of I. suffruticosa in cattle food, careful evaluation must be done.
Full text:
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Index:
LILACS (Americas)
Main subject:
Plants, Medicinal
/
Plant Extracts
/
Animal Feed
Limits:
Animals
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
1991
Type:
Article
/
Congress and conference
Affiliation country:
Brazil
Institution/Affiliation country:
Empresa de Pesquisa Agropecuária da Bahia/BR
/
UFBA/BR
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