Anti-schistosomiasis triterpene glycoside from the Egyptian medicinal plant Asparagus stipularis
Rev. bras. farmacogn
;
22(2): 314-318, Mar.-Apr. 2012. ilus, tab
Article
in English
| LILACS
| ID: lil-624670
ABSTRACT
Bioassay-guided isolation using an in vitro assay testing for anti- schistosomiasis yielded a novel triterpene saponin, asparagalin A, from the n-butanol extract of the roots of Asparagus stipularis Forssk., Asparagaceae. The structure was elucidated by spectroscopic analysis and chemical transformations. Administration of asparagalin A resulted in a retardation of worm growth and locomotion at the first day and showed a significant activity of egg-laying suppression at 200 µg/mL concentration.
Full text:
Available
Index:
LILACS (Americas)
Language:
English
Journal:
Rev. bras. farmacogn
Journal subject:
Pharmacy
Year:
2012
Type:
Article
/
Project document
Affiliation country:
Egypt
/
Sweden
Institution/Affiliation country:
Alexandria University/EG
/
Desert Research Centre/EG
/
El-Menoufia University/EG
/
National Research Centre/EG
/
Royal Institute of Technology KTH/SE
/
Uppsala University/SE
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