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Manejo de la hiperglucemia en el paciente hospitalizado / Management of hyperglycemia in the hospitalized patient
Pasquel, Francisco J.; Umpierrez, Guillermo E..
  • Pasquel, Francisco J.; Emory University School of Medicine. Department of Medicine. Atlanta. US
  • Umpierrez, Guillermo E.; Emory University School of Medicine. Department of Medicine. Atlanta. US
Medicina (B.Aires) ; 70(3): 275-283, mayo-jun. 2010. tab
Article in Spanish | LILACS | ID: lil-633753
RESUMEN
La hiperglucemia es una manifestación frecuente en los pacientes hospitalizados dentro y fuera de la unidad de cuidados intensivos. La hiperglucemia se asocia, a su vez, con un aumento en la morbilidad, la mortalidad y la estancia hospitalaria. Los mecanismos causantes de estas complicaciones no están claros, pero se ha reconocido que múltiples procesos fisiológicos son afectados durante el aumento de la glucemia. Estudios prospectivos han demostrado un impacto positivo del control de los niveles de glucosa sobre varios parámetros clínicos y la mortalidad en diferentes grupos de pacientes críticos; sin embargo, las metas de control glucémico en los pacientes hospitalizados han sido cuestionadas. En consecuencia, muchos profesionales de la salud no tienen una aproximación bien formulada y objetiva para manejar la hiperglucemia en el hospital. En este artículo revisamos estudios observacionales y prospectivos relacionados a la hiperglucemia en pacientes hospitalizados, además de las opciones de manejo de la hiperglucemia y recomendaciones para la transición al control ambulatorio.
ABSTRACT
Hyperglycemia is a frequent complication in patients admitted to the hospital, and it is associated with increased morbidity, mortality and length of stay. The mechanisms that cause these complications are not clear, but multiple physiological processes are affected with increased glucose levels. Prospective studies have showed a positive impact of glucose control on morbidity, and mortality in different groups of patients. However, questions have risen regarding glucose targets, and consequently many healthcare providers do not have a well-formulated and objective approach to handle hyperglycemia in critically, and non-critically ill patients. In this article we review observational and prospective studies regarding hyperglycemia in the hospital. We also describe options for glucose control, and recommendations for the transition of glucose management to the ambulatory setting.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Critical Illness / Critical Care / Hospitalization / Hyperglycemia / Hypoglycemic Agents / Insulin Type of study: Practice guideline / Observational study / Risk factors Limits: Humans Country/Region as subject: North America Language: Spanish Journal: Medicina (B.Aires) Journal subject: Medicine Year: 2010 Type: Article Affiliation country: United States Institution/Affiliation country: Emory University School of Medicine/US

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Full text: Available Index: LILACS (Americas) Main subject: Critical Illness / Critical Care / Hospitalization / Hyperglycemia / Hypoglycemic Agents / Insulin Type of study: Practice guideline / Observational study / Risk factors Limits: Humans Country/Region as subject: North America Language: Spanish Journal: Medicina (B.Aires) Journal subject: Medicine Year: 2010 Type: Article Affiliation country: United States Institution/Affiliation country: Emory University School of Medicine/US