Quimerismo genético un nuevo paradigma para la medicina legal / Genetic chimerism a new paradigm for legal medicine
Med. leg. Costa Rica
;
26(2): 73-78, sep. 2009.
Article
in Spanish
| LILACS
| ID: lil-637483
RESUMEN
El quimerismo genético un concepto no bien esclarecido en la comunidad científica, aún confundido con mosaicismo. En la presente revisión pretendemos definirlo con un enfoque legal y ejemplificarlo con una serie de casos descritos en la literatura médica, los cuales nos orientan a la diferencia clara entre mosaicismo y quimerismo. Dentro de esta serie separamos los casos que se relacionan con hermafroditismo y los no relacionados. Además, hacemos referencia a un nuevo concepto que genera polémica en la investigación, el microquimerismo, relacionado con transfusiones sanguíneas, transplantes y la génesis de las enfermedades autoinmunes.
ABSTRACT
Genetic chimerism is a not well defined concept among the scientific community; it is still confused with mosaicism. In the following review we intend to define the concept with a legal point of view and exemplify it with a series of cases described in medical texts. The cases lead us to find the clear difference between mosaicism and chimerism. Contained in these series of cases we have separated the ones related with hemaphroditism from the ones that are not related. We also make reference to a new concept that generates controversy in the investigation; microchimerism, which is related with blood transfusions, transplants and genesis of autoimmune diseases..
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Disorders of Sex Development
/
Sex Chromosome Disorders
/
Chimerism
/
Jurisprudence
/
Mosaicism
Limits:
Humans
Country/Region as subject:
Central America
/
Costa Rica
Language:
Spanish
Journal:
Med. leg. Costa Rica
Journal subject:
Jurisprudence
Year:
2009
Type:
Article
Affiliation country:
Costa Rica
Institution/Affiliation country:
Universidad de Costa Rica/CR
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