Detection of Lsr2 gene of Mycobacterium leprae in nasal mucus
Braz. arch. biol. technol
;
55(3): 375-380, May-June 2012. tab
Article
in English
| LILACS
| ID: lil-640187
ABSTRACT
In the present study, nasal mucus from patients with leprosy were analyzed by PCR using specific primers for Lsr2 gene of Mycobacterium leprae. The presence of Lsr2 gene in the nasal mucus was detected in 25.80% of patients with paucibacillari leprosy, and 23.07% of contacts. Despite the absence of clinical features in the contact individuals, it was possible to detect the presence of Lsr2 gene in the nasal mucus of these individuals. Therefore, PCR detection of M. leprae targeting Lsr2 gene using nasal mucus samples could contribute to early diagnosis of leprosy.
Full text:
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Index:
LILACS (Americas)
Type of study:
Diagnostic study
/
Screening study
Language:
English
Journal:
Braz. arch. biol. technol
Journal subject:
Biology
Year:
2012
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Estadual de Londrina/BR
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