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The diameter of the originating vein determines esophageal and gastric fundic varices in portal hypertension secondary to posthepatitic cirrhosis
Zhou, Hai-ying; Chen, Tian-wu; Zhang, Xiao-ming; Wang, Li-ying; Zhou, Li; Dong, Guo-li; Zeng, Nan-lin; Li, Hang; Chen, Xiao-li; Li, Rui.
  • Zhou, Hai-ying; Affiliated Hospital of North Sichuan Medical College. Department of Radiology. Sichuan Key Laboratory of Medical Imaging. Sichuan. CN
  • Chen, Tian-wu; Affiliated Hospital of North Sichuan Medical College. Department of Radiology. Sichuan Key Laboratory of Medical Imaging. Sichuan. CN
  • Zhang, Xiao-ming; Affiliated Hospital of North Sichuan Medical College. Department of Radiology. Sichuan Key Laboratory of Medical Imaging. Sichuan. CN
  • Wang, Li-ying; Affiliated Hospital of North Sichuan Medical College. Department of Radiology. Sichuan Key Laboratory of Medical Imaging. Sichuan. CN
  • Zhou, Li; Affiliated Hospital of North Sichuan Medical College. Department of Radiology. Sichuan Key Laboratory of Medical Imaging. Sichuan. CN
  • Dong, Guo-li; Affiliated Hospital of North Sichuan Medical College. Department of Radiology. Sichuan Key Laboratory of Medical Imaging. Sichuan. CN
  • Zeng, Nan-lin; Affiliated Hospital of North Sichuan Medical College. Department of Radiology. Sichuan Key Laboratory of Medical Imaging. Sichuan. CN
  • Li, Hang; Affiliated Hospital of North Sichuan Medical College. Department of Radiology. Sichuan Key Laboratory of Medical Imaging. Sichuan. CN
  • Chen, Xiao-li; Affiliated Hospital of North Sichuan Medical College. Department of Radiology. Sichuan Key Laboratory of Medical Imaging. Sichuan. CN
  • Li, Rui; Affiliated Hospital of North Sichuan Medical College. Department of Radiology. Sichuan Key Laboratory of Medical Imaging. Sichuan. CN
Clinics ; 67(6): 609-614, 2012.
Article in English | LILACS | ID: lil-640211
ABSTRACT

OBJECTIVE:

The aim of this study was to determine whether and how the diameter of the vein that gives rise to the inflowing vein of the esophageal and gastric fundic varices secondary to posthepatitic cirrhosis, as measured with multidetector-row computed tomography, could predict the varices and their patterns.

METHODS:

A total of 106 patients with posthepatitic cirrhosis underwent multidetector-row computed tomography. Patients with and without esophageal and gastric fundic varices were enrolled in Group 1 and Group 2, respectively. Group 1 was composed of Subgroup A, consisting of patients with varices, and Subgroup B consisted of patients with varices in combination with portal vein-inferior vena cava shunts. The diameters of the originating veins of veins entering the varices were reviewed and statistically analyzed.

RESULTS:

The originating veins were the portal vein in 8% (6/75) of patients, the splenic vein in 65.3% (49/75) of patients, and both the portal and splenic veins in 26.7% (20/75) of patients. The splenic vein diameter in Group 1 was larger than that in Group 2, whereas no differences in portal vein diameters were found between groups. In Group 1, the splenic vein diameter in Subgroup A was larger than that in Subgroup B. A cut-off splenic vein diameter of 8.5 mm achieved a sensitivity of 83.3% and specificity of 58.1% for predicting the varices. For discrimination of the varices in combination with and without portal vein-inferior vena cava shunts, a cut-off diameter of 9.5 mm achieved a sensitivity of 66.7% and specificity of 60.0%.

CONCLUSION:

The diameter of the splenic vein can be used to predict esophageal and gastric fundic varices and their patterns.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Portal Vein / Splenic Vein / Esophageal and Gastric Varices / Hypertension, Portal / Liver Cirrhosis Type of study: Etiology study / Prognostic study Limits: Adolescent / Adult / Aged / Female / Humans / Male Language: English Journal: Clinics Journal subject: Medicine Year: 2012 Type: Article Affiliation country: China Institution/Affiliation country: Affiliated Hospital of North Sichuan Medical College/CN

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Full text: Available Index: LILACS (Americas) Main subject: Portal Vein / Splenic Vein / Esophageal and Gastric Varices / Hypertension, Portal / Liver Cirrhosis Type of study: Etiology study / Prognostic study Limits: Adolescent / Adult / Aged / Female / Humans / Male Language: English Journal: Clinics Journal subject: Medicine Year: 2012 Type: Article Affiliation country: China Institution/Affiliation country: Affiliated Hospital of North Sichuan Medical College/CN