Initial stage of development and migratory behavior of Toxocara canis larvae in BALB/c mouse experimental model
Genet. mol. res. (Online)
;
7(2): 444-450, 2008. tab, ilus
Article
in English
| LILACS
| ID: lil-640994
ABSTRACT
In the present study, the initial developmental stage of Toxocara canis eggs and larvae, and number of recovered larvae from BALB/c mouse-infected organs are described. In vitro culture of T. canis detects the frequencies of interphasic, mitotic and embryonated eggs only within a 7-day period. Analysis by egg counting was carried out for 32 days. The results showed that at 7 days after cultivation, the frequency of larvae was 50.4% and that this frequency reached 52.8% in 32 days. In the experimental infection of BALB/c mice with T. canis, the number of recovered larvae statistically increased in the brain and liver, with doses of approximately 200 and 1000 eggs. After 7 days of infection, a larger number of larvae were obtained in the lung and liver, although a maximum amount was found in the brain after a 15- or 30-day post-infection period.
Full text:
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Index:
LILACS (Americas)
Main subject:
Parasite Egg Count
/
Toxocariasis
/
Toxocara canis
Type of study:
Prognostic study
Limits:
Animals
Language:
English
Journal:
Genet. mol. res. (Online)
Journal subject:
Molecular Biology
/
Genetics
Year:
2008
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Estadual de Maringá/BR
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