Hepatitis C virus quantification in serum and saliva of HCV-infected patients
Mem. Inst. Oswaldo Cruz
;
107(5): 680-683, Aug. 2012. graf, tab
Article
in English
| LILACS
| ID: lil-643755
ABSTRACT
The hepatitis C virus (HCV) can be detected in blood and other bodily fluids, such as saliva, semen and gastric juices. The aim of this study was to compare the HCV viral loads in the serum and saliva of infected patients. Twenty-nine patients with detectable HCV RNA in their serum and saliva were included in this study. The HCV viral loads were determined through quantitative real-time polymerase chain reactions. The median viral RNA levels were 5.78 log10 copies in the serum and 3.32 log10 copies in the saliva. We observed that the salivary HCV viral load was significantly lower than the viral load in the serum. Further studies are required to understand the role of saliva in the diagnosis, management and potential transmission of HCV.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Saliva
/
Hepacivirus
/
Hepatitis C, Chronic
/
Serum
Type of study:
Observational study
/
Prevalence study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2012
Type:
Article
/
Project document
Affiliation country:
Brazil
Institution/Affiliation country:
Laboratório de Patologia e Biologia Molecular-Fiocruz/BR
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