Hepatitis autoinmune en niños: diagnostico / Autoimmune hepatitis in children: diagnosis
Rev. GASTROHNUP
;
12(2, Supl.1): S20-S24, mayo-ago. 2010. tab
Article
in Spanish
| LILACS
| ID: lil-645159
RESUMEN
El diagnóstico de la hepatitis autoinmune (HAI), se basa en una serie de criterios definidos por elGrupo Internacional de HAI (IAIHG) que permite clasificarla como HAI probable o definitiva. Un criterio clave para el diagnóstico de la HAI es la detección de ANA, SMA, y anti- LKM-1 por inmunofluorescencia indirecta. Otros anticuerpos menos frecuentes probados, pero de importancia diagnóstica en HAI pediátrica incluyen los anticuerpos tipo citosol 1 hígado (LC-1), anti- citoplasma de los neutrófilos (ANCA) y el antígeno soluble hepático (SLA). La Ig G está usualmente elevada en ambos tipos de HAI, cerca del 15% de niños con HAI I y el 25% de niños con HAI tipo II tienen valores normales. La biopsia hepática es necesaria para establecer el diagnóstico de HAI.
ABSTRACT
The diagnosis of autoimmune hepatitis (HAI), is based on a set of criteria defined by the International HAI Group (IAIHG) that allows classified as a probable or definite HAI. A key criterion for the diagnosis of HAI is the detection of ANA, SMA, and anti-LKM-1 by indirectimmunofluorescence. Other less common antibodies tested, but important diagnostic tool in pediatric HAI include antibodies such as liver cytosol 1 (LC-1), anti-neutrophil cytoplasmic (ANCA) and soluble liver antigen (SLA). The Ig G is usually high in both types of HAI, about 15% of children with HAI I and 25% of children with HAI type II are normal. Liver biopsy is necessary to establish the diagnosis of HAI.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Hepatitis, Autoimmune
Type of study:
Diagnostic study
Limits:
Child
/
Female
/
Humans
/
Male
Language:
Spanish
Journal:
Rev. GASTROHNUP
Journal subject:
Nutritional Sciences
/
Pediatrics
Year:
2010
Type:
Article
Affiliation country:
Colombia
Institution/Affiliation country:
Universidad Industrial de Santander/CO
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