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Thyroid nodules in acromegaly / Nódulos tiroideanos na acromegalia
Rogozinski, Amelia; Furioso, Alejandra; Glikman, Patricia; Junco, Marcelo; Laudi, Rosa; Reyes, Adriana; Lowenstein, Alicia.
  • Rogozinski, Amelia; Hospital J. M. Ramos Mejía. Buenos Aires. AR
  • Furioso, Alejandra; Hospital J. M. Ramos Mejía. Buenos Aires. AR
  • Glikman, Patricia; Hospital J. M. Ramos Mejía. Buenos Aires. AR
  • Junco, Marcelo; Hospital J. M. Ramos Mejía. Buenos Aires. AR
  • Laudi, Rosa; Hospital J. M. Ramos Mejía. Buenos Aires. AR
  • Reyes, Adriana; Hospital J. M. Ramos Mejía. Buenos Aires. AR
  • Lowenstein, Alicia; Hospital J. M. Ramos Mejía. Buenos Aires. AR
Arq. bras. endocrinol. metab ; 56(5): 300-304, jul. 2012. tab
Article in English | LILACS | ID: lil-646317
ABSTRACT

OBJECTIVE:

We made a prospective study evaluating the prevalence of thyroid nodular disease in acromegalic patients. SUBJECTS AND

METHODS:

Thyroid ultrasound and ultrasound-guided fine needle aspiration biopsy were performed when nodules were detected. Nodules were characterized by cytology and histopathology.

RESULTS:

We found high prevalence of nodular thyroid disorder, 23/34 (67%) in acromegalic patients. High risk and malignant cytology were significantly higher in acromegalic patients than in our non-acromegalic population (25% vs. 9%). Differentiated thyroid carcinoma was present in 11% of the acromegalic patients.

CONCLUSIONS:

We strongly recommend periodic thyroid evaluation by ultrasound in patients with acromegaly. Fine needle aspiration biopsy should be performed in nodules larger than 10 mm, and in all suspicious nodules, regardless of the size.
RESUMO

OBJETIVO:

Realizamos um estudo prospectivo avaliando a prevalência de patologia nodular tireói­dea em 34 pacientes acromegálicos. SUJEITOS E

MÉTODOS:

Avaliamos os pacientes com ecografia tireóidea e punção biópsia com agulha fina quando se detectavam nódulos.

RESULTADOS:

Encontramos uma alta prevalência de patologia nodular tireóidea 23/34 (67%) em acromegálicos. A citologia tireóidea de alto risco e maligna foi significativamente mais elevada em pacientes acromegálicos que em uma população não acromegálica (25% vs. 9%). O grupo acromegálico apresentou carcinoma diferenciado de tireoides em 11%.

CONCLUSÕES:

Recomendamos fortemente a ecografia periódica tireóidea em pacientes acromegálicos. Uma punção biópsia aspirativa com agulha fina deve ser realizada em presença de nódulos tireóideos maiores que 10 mm e daqueles com critérios ecográficos suspeitos de malignidade, independentemente do tamanho deles.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Thyroid Gland / Acromegaly / Thyroid Nodule Type of study: Observational study / Risk factors Limits: Adult / Aged / Aged80 / Female / Humans / Male Language: English Journal: Arq. bras. endocrinol. metab Journal subject: Endocrinology / Metabolism Year: 2012 Type: Article Affiliation country: Argentina Institution/Affiliation country: Hospital J. M. Ramos Mejía/AR

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Full text: Available Index: LILACS (Americas) Main subject: Thyroid Gland / Acromegaly / Thyroid Nodule Type of study: Observational study / Risk factors Limits: Adult / Aged / Aged80 / Female / Humans / Male Language: English Journal: Arq. bras. endocrinol. metab Journal subject: Endocrinology / Metabolism Year: 2012 Type: Article Affiliation country: Argentina Institution/Affiliation country: Hospital J. M. Ramos Mejía/AR