Unexplained Male infertility: diagnosis and Management
Int. braz. j. urol
;
38(5): 576-594, Sept.-Oct. 2012. ilus
Article
in English
| LILACS
| ID: lil-655985
ABSTRACT
Unexplained male infertility is a diagnosis reserved for men in whom routine semen analyses results are within normal values and physical as well as endocrine abnormalities were ruled out. In addition to erectile problems and coital factors, immunologic causes and sperm dysfunction may contribute to such condition. New etiologies of unexplained male infertility include low level leukocytospermia and mitochondrial DNA polymerase gene polymorphism. Contemporary andrology may reveal cellular and sub-cellular sperm dysfunctions which may explain subfertility in such cases, thus aiding the clinician to direct the further work-up, diagnosis and counseling of the infertile male. The objective of this article is to highlight the concept of unexplained male infertility and focuses on the diagnosis and treatment of this condition in the era of modern andrology and assisted reproductive techniques. Extensive literature review was performed using the search engines Pubmed, Science-direct, Ovid and Scopus.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Semen Analysis
/
Infertility, Male
Type of study:
Diagnostic study
/
Etiology study
Limits:
Humans
/
Male
Language:
English
Journal:
Int. braz. j. urol
Journal subject:
Urology
Year:
2012
Type:
Article
Affiliation country:
United States
Institution/Affiliation country:
Glickman Urological and Kidney Institute/US
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