Historic aspects of human susceptibility to leprosy and the risk of conjugal transmission
Mem. Inst. Oswaldo Cruz
;
107(supl.1): 17-21, Dec. 2012. tab
Article
in English
| LILACS
| ID: lil-659735
ABSTRACT
Estimates of genetic susceptibility to leprosy were made in the past from observational reports in familial settings using descriptive epidemiologic data. Risk of conjugal transmission of leprosy (from one spouse to another) has been estimated between 1-10% and is thought to occur in 3-5% of spouses exposed to untreated lepromatous disease in the partner. Risk of secondary transmission is presumed higher in other family members than for the conjugal partner. This belief has become dogma to many leprologists who may no longer know the basis for this estimation. This article reviews the historic epidemiologic descriptions of risk for leprosy transmission in married couples compared to other family members. Although uncommon, conjugal leprosy occurs and at higher rates in populations with traditional familial intermarriage and consanguinity.
Full text:
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Index:
LILACS (Americas)
Main subject:
Spouses
/
Leprosy
Type of study:
Etiology study
/
Risk factors
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2012
Type:
Article
Affiliation country:
United States
Institution/Affiliation country:
Centers for Disease Control and Prevention/US
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