Encefalitis autoinmune reversible y anticuerpos anti-receptores de N-metil-D-aspartato: Report of one case / Limbic encephalitis with positive anti-N-methyl-D-aspartate antibodies
Rev. méd. Chile
;
140(9): 1170-1173, set. 2012.
Article
in Spanish
| LILACS
| ID: lil-660075
ABSTRACT
Background:
Limbic encephalitis is a subacute syndrome characterized by memory impairment, confusion, seizures, hypothalamic dysfunction and psychiatric symptoms. It has been associated to tumors located outside of the central nervous system. In 2007, anti-N-methyl-D-aspartate receptors (NMDAr) antibodies were found in serum and CSF of patients with this particular type of encephalitis. We report a 25-year-old female who, following upper respiratory tract symptoms, developed serious behavioral and consciousness impairment that progressed to coma. Cerebrospinal fluid (CSF) analysis showed a lymphocyte pleocytosis, the electroencephalogram was altered with a slow encephalopathic rhythm and a brain magnetic resonance imaging was normal. Infectious etiologies were ruled out. CSF and serum anti NMDA receptors antibodies were positive.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
N-Methylaspartate
/
Receptors, N-Methyl-D-Aspartate
/
Limbic Encephalitis
/
Antibodies
Limits:
Adult
/
Female
/
Humans
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2012
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Universidad de Chile/CL
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