The effects of exercise modalities on adiposity in obese rats
Clinics
;
67(12): 1469-1477, Dec. 2012. ilus, tab
Article
in English
| LILACS
| ID: lil-660477
ABSTRACT
OBJECTIVE:
The aim of the present study was to evaluate the effect of both swimming and resistance training on tumor necrosis factor-alpha and interleukin-10 expression, adipocyte area and lipid profiles in rats fed a high-fat diet.METHODS:
The study was conducted over an eight-week period on Wistar adult rats, who were divided into six groups as follows (n = 10 per group) sedentary chow diet, sedentary high-fat diet, swimming plus chow diet, swimming plus high-fat diet, resistance training plus chow diet, and resistance training plus high-fat diet. Rats in the resistance training groups climbed a vertical ladder with weights on their tails once every three days. The swimming groups swam for 60 minutes/day, five days/week.RESULTS:
The high-fat diet groups had higher body weights, a greater amount of adipose tissue, and higher tumor necrosis factor-alpha expression in the visceral adipose tissue. Furthermore, the high-fat diet promoted a negative change in the lipid profile. In the resistance training high-fat group, the tumor necrosis factor-alpha expression was lower than that in the swimming high-fat and sedentary high-fat groups. Moreover, smaller visceral and retroperitoneal adipocyte areas were found in the resistance training high-fat group than in the sedentary high-fat group. In the swimming high-fat group, the tumor necrosis factor-alpha expression was lower and the epididymal and retroperitoneal adipocyte areas were smaller compared with the sedentary high-fat group.CONCLUSION:
The results showed that both exercise modalities improved the lipid profile, adiposity and obesity-associated inflammation in rats, suggesting their use as an alternative to control the deleterious effects of a high-fat diet in humans.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Physical Conditioning, Animal
/
Tumor Necrosis Factor-alpha
/
Adiposity
/
Lipid Metabolism
/
Diet, High-Fat
Type of study:
Prognostic study
/
Systematic reviews
Limits:
Animals
Language:
English
Journal:
Clinics
Journal subject:
Medicine
Year:
2012
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Federal University of São Carlos/BR
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