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Incidence of angiolymphatic invasion in colorectal cancer
Lopes, Renan Cascaes; Silveira Junior, Sergio; Koch, Kaiser de Souza.
  • Lopes, Renan Cascaes; Universidade do Sul. Medical School. Tubarão. BR
  • Silveira Junior, Sergio; Unisul. Medical School. Tubarão. BR
  • Koch, Kaiser de Souza; Unisul. Tubarão. BR
J. coloproctol. (Rio J., Impr.) ; 32(3): 240-245, July-Sept. 2012. graf, tab
Article in English | LILACS | ID: lil-660609
ABSTRACT
Angiolymphatic invasion (ALI) in colorectal cancer (CRC) is considered as an important independent prognostic factor and may influence therapeutic decisions.

OBJECTIVE:

This aim of the study is to find the incidence of ALI in histopathological reports of surgical specimens from patients who underwent surgical treatment of colorectal adenocarcinoma.

RESULTS:

One hundred and twenty seven patients were male (50.6%) and the mean age was 60 years old. The overall incidence of ALI was 44.6%, and there was a significant association with age (p=0.016), lymph node involvement (N) (p<0.00001) and tumor differentiation (p=0.0039).

CONCLUSION:

There was a higher probability of finding ALI in younger patients, with a higher number of lymph node metastases and a lower tumor differentiation. (AU)
RESUMO
A invasão angiolinfática (LVI) no câncer colorretal (CCR) é considerada um importante marcador independente de prognóstico e pode influenciar em decisões terapêuticas.

OBJETIVO:

Encontrar a incidência de LVI através de laudos histopatológicos de peças operatórias de pacientes submetidos a tratamento cirúrgico de câncer colorretal, por adenocarcinoma.

RESULTADOS:

A média de idade encontrada foi de 60,08 anos. Cento e vinte sete pacientes eram do sexo masculino (50,6%). A incidência global de LVI foi de 44,6% e houve associação significativa com a idade (p=0,016), o grau de acometimento linfonodal (N) (p<0,00001) e o grau de diferenciação (p=0,0039).

CONCLUSÃO:

Há uma maior probabilidade de encontrarmos LVI em pacientes mais novos, com um número maior de linfonodos acometidos e um menor grau de diferenciação celular. (AU)
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Rectal Neoplasms / Adenocarcinoma / Colonic Neoplasms Type of study: Incidence study / Prognostic study / Risk factors Limits: Aged / Female / Humans / Male Language: English Journal: J. coloproctol. (Rio J., Impr.) Journal subject: Cirurgia / Doen‡as Retais / Doen‡as do Colo / Gastroenterology / Cirurgia Year: 2012 Type: Article Affiliation country: Brazil Institution/Affiliation country: Unisul/BR / Universidade do Sul/BR

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Full text: Available Index: LILACS (Americas) Main subject: Rectal Neoplasms / Adenocarcinoma / Colonic Neoplasms Type of study: Incidence study / Prognostic study / Risk factors Limits: Aged / Female / Humans / Male Language: English Journal: J. coloproctol. (Rio J., Impr.) Journal subject: Cirurgia / Doen‡as Retais / Doen‡as do Colo / Gastroenterology / Cirurgia Year: 2012 Type: Article Affiliation country: Brazil Institution/Affiliation country: Unisul/BR / Universidade do Sul/BR