Incidence of angiolymphatic invasion in colorectal cancer
J. coloproctol. (Rio J., Impr.)
;
32(3): 240-245, July-Sept. 2012. graf, tab
Article
in English
| LILACS
| ID: lil-660609
ABSTRACT
Angiolymphatic invasion (ALI) in colorectal cancer (CRC) is considered as an important independent prognostic factor and may influence therapeutic decisions. OBJECTIVE:
This aim of the study is to find the incidence of ALI in histopathological reports of surgical specimens from patients who underwent surgical treatment of colorectal adenocarcinoma.RESULTS:
One hundred and twenty seven patients were male (50.6%) and the mean age was 60 years old. The overall incidence of ALI was 44.6%, and there was a significant association with age (p=0.016), lymph node involvement (N) (p<0.00001) and tumor differentiation (p=0.0039).CONCLUSION:
There was a higher probability of finding ALI in younger patients, with a higher number of lymph node metastases and a lower tumor differentiation. (AU)RESUMO
A invasão angiolinfática (LVI) no câncer colorretal (CCR) é considerada um importante marcador independente de prognóstico e pode influenciar em decisões terapêuticas. OBJETIVO:
Encontrar a incidência de LVI através de laudos histopatológicos de peças operatórias de pacientes submetidos a tratamento cirúrgico de câncer colorretal, por adenocarcinoma.RESULTADOS:
A média de idade encontrada foi de 60,08 anos. Cento e vinte sete pacientes eram do sexo masculino (50,6%). A incidência global de LVI foi de 44,6% e houve associação significativa com a idade (p=0,016), o grau de acometimento linfonodal (N) (p<0,00001) e o grau de diferenciação (p=0,0039).CONCLUSÃO:
Há uma maior probabilidade de encontrarmos LVI em pacientes mais novos, com um número maior de linfonodos acometidos e um menor grau de diferenciação celular. (AU)
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Rectal Neoplasms
/
Adenocarcinoma
/
Colonic Neoplasms
Type of study:
Incidence study
/
Prognostic study
/
Risk factors
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
J. coloproctol. (Rio J., Impr.)
Journal subject:
Cirurgia
/
Doenas Retais
/
Doenas do Colo
/
Gastroenterology
/
Cirurgia
Year:
2012
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Unisul/BR
/
Universidade do Sul/BR
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