Effect of an acrylic resin combined with an antimicrobial polymer on biofilm formation
J. appl. oral sci
;
20(6): 643-648, Nov.-Dec. 2012. ilus, tab
Article
in English
| LILACS
| ID: lil-660635
ABSTRACT
OBJECTIVES:
The purpose of this study was to evaluate the antimicrobial activity of an acrylic resin combined with an antimicrobial polymer poly (2-tert-butylaminoethyl) methacrylate (PTBAEMA) to inhibit Staphylococcus aureus, Streptococcus mutans and Candida albicans biofilm formation. MATERIAL ANDMETHODS:
Discs of a heat-polymerized acrylic resin were produced and divided according to PTBAEMA concentration 0 (control), 10 and 25%. The specimens were inoculated (10(7) CFU/mL) and incubated at 37ºC for 48 h. After incubation, the wells were washed and each specimen was sonicated for 20 min. Replicate aliquots of resultant suspensions were plated at dilutions at 37ºC for 48 h. The number of colony-forming units (CFU) was counted and expressed as log (CFU+1)/mL and analyzed statistically with α=.05.RESULTS:
The results showed that 25% PTBAEMA completely inhibited S. aureus and S. mutans biofilm formation. A significant reduction of log (CFU+1)/mL in count of S. aureus (control 7.9±0.8A; 10% 3.8±3.3B) and S. mutans (control 7.5±0.7A; 10% 5.1±2.7B) was observed for the group containing 10% PTBAEMA (Mann-Whitney, p<0.05). For C. albicans, differences were not significant among the groups (control 6.6±0.2A; 10% 6.6±0.4A; 25% 6.4±0.1A), (Kruskal-Wallis, p>0.05, P=0.079).CONCLUSIONS:
Acrylic resin combined with 10 and 25% of PTBAEMA showed significant antimicrobial activity against S. aureus and S. mutans biofilm, but it was inactive against the C. albicans biofilm.
Full text:
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Index:
LILACS (Americas)
Main subject:
Staphylococcus aureus
/
Streptococcus mutans
/
Acrylic Resins
/
Candida albicans
/
Biofilms
/
Methacrylates
Language:
English
Journal:
J. appl. oral sci
Journal subject:
Dentistry
Year:
2012
Type:
Article
/
Project document
Affiliation country:
Brazil
Institution/Affiliation country:
Paulista University/BR
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