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Spinal anesthesia for elective ceasarean section: use of different doses of hyperbaric bupivacaine associated with morphine and clonidine
Braga, Angélica de Fátima de Assunção; Frias, José Aristeu Fachini; Braga, Franklin Sarmento da Silva; Pereira, Rosa Inês Costa; Titotto, Stella Marys Meirelles Campos.
  • Braga, Angélica de Fátima de Assunção; UNICAMP. Department of Anesthesiology. Campinas. BR
  • Frias, José Aristeu Fachini; UNICAMP. Department of Anesthesiology. Campinas. BR
  • Braga, Franklin Sarmento da Silva; UNICAMP. Department of Anesthesiology. Campinas. BR
  • Pereira, Rosa Inês Costa; UNICAMP. Department of Anesthesiology. Campinas. BR
  • Titotto, Stella Marys Meirelles Campos; UNICAMP. Department of Anesthesiology. Campinas. BR
Acta cir. bras ; 28(1): 26-32, jan. 2013. tab
Article in English | LILACS | ID: lil-662344
ABSTRACT

PURPOSE:

To comparatively study the efficacy and maternal and fetal side-effects of two doses of bupivacaine associated with morphine and clonidine, administered by the subarachnoid route for cesarean section.

METHODS:

The study included 66 pregnant women at term, distributed into two groups. GI bupivacaine 8.0 mg (1.6mL) + clonidine 75µg (0.5mL) + morphine 100µg (1.0mL) and GII bupivacaine 10mg (2.0mL) + clonidine 75µg (0.5mL) + morphine 100µg (1.0mL). The following parameters were assessed onset and maximum level of sensory block; quality of intraoperative and postoperative analgesia; degree and duration of motor block; maternal repercussions and Apgar score.

RESULTS:

The onset of sensory block, quality of intraoperative analgesia and total duration of analgesia were similar in both groups; maximum extent of sensory block predominated in T4; maximum degree of motor block (Bromage 3); time motor block regression was significantly longer in GII; Hemodynamic, respiratory repercussions, adverse maternal effects and Apgar scores were similar between groups. In both groups, there was a predominance of drowsy or sleeping patients.

CONCLUSION:

The addition of morphine and clonidine to low doses of hyperbaric bupivacaine produced adequate anesthesia for cesarean section and good postoperative analgesia, without any maternal and fetal repercussions.
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Full text: Available Index: LILACS (Americas) Main subject: Bupivacaine / Cesarean Section / Clonidine / Anesthetics, Combined / Anesthesia, Spinal / Morphine Type of study: Controlled clinical trial / Risk factors Limits: Adult / Female / Humans / Pregnancy Language: English Journal: Acta cir. bras Journal subject: General Surgery / Procedimentos Cir£rgicos Operat¢rios Year: 2013 Type: Article Affiliation country: Brazil Institution/Affiliation country: UNICAMP/BR

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Full text: Available Index: LILACS (Americas) Main subject: Bupivacaine / Cesarean Section / Clonidine / Anesthetics, Combined / Anesthesia, Spinal / Morphine Type of study: Controlled clinical trial / Risk factors Limits: Adult / Female / Humans / Pregnancy Language: English Journal: Acta cir. bras Journal subject: General Surgery / Procedimentos Cir£rgicos Operat¢rios Year: 2013 Type: Article Affiliation country: Brazil Institution/Affiliation country: UNICAMP/BR