Your browser doesn't support javascript.
loading
A retrospective study of oral manifestations in patients with paracoccidioidomycosis
Azenha, Marcelo Rodrigues; Caliento, Rubens; Brentegani, Luiz Guilherme; Lacerda, Suzie Aparecida de.
  • Azenha, Marcelo Rodrigues; University of São Paulo. Ribeirão Preto Dental School. Department of Stomatology. Ribeirão Preto. BR
  • Caliento, Rubens; University of São Paulo. Ribeirão Preto Dental School. Department of Stomatology. Ribeirão Preto. BR
  • Brentegani, Luiz Guilherme; University of São Paulo. Ribeirão Preto Dental School. Department of Stomatology. Ribeirão Preto. BR
  • Lacerda, Suzie Aparecida de; University of São Paulo. Ribeirão Preto Dental School. Department of Stomatology. Ribeirão Preto. BR
Braz. dent. j ; 23(6): 753-757, 2012. ilus
Article in English | LILACS | ID: lil-662438
ABSTRACT
South American blastomycosis, paracoccidioidomycosis (Pb mycosis) or Lutz disease is an endemically fungal infection in Latin America. It is caused by the dimorphic fungus Paracoccidioides brasiliensis and may cause oral mucosal lesions. The incidence of Pb mycosis oral lesions was evaluated in patients assisted at a Brazilian Dental School's Specialized Oral Diagnosis Service with special focus on the different clinical forms of these lesions, its location, patients' occupation, deleterious habits, and diagnosis methodology. Students' and professionals' initial diagnoses were compared with the definitive diagnosis. Lesions were detected 31 cases (18 patients). The results show that 88.8% of the patients were male with a mean age of 50 years and 39% work(ed) with activities related to agriculture. As much as 88.9% were smokers and 72.2% were alcohol users. Exfoliative cytology was performed in 66.6% of the patients. Oral mucosa (30%), gingiva (16.6%) and lips 16.6% were the most common sites of Pb mycosis oral lesions. Comparing the initial with the definitive diagnosis made by the professionals their accuracy was 33% (6 out of 18 patients). Students' diagnosis was more accurate demonstrating 72.5% of initial correct diagnosis (13 out of 18). Statistical analysis by ANOVA (α=0.05, SPSS WIN) demonstrated a significant difference between the diagnosis of Pb mycosis made by students and professionals when considering initial diagnosis and final diagnosis (after histopathological analysis) (p=0.25). Incisional biopsy and exfoliate cytology are efficient for an early diagnosis of this disease in mouth. Students' training in diagnosis of oral pathologies to recognize lesions is urgent to improve public health.
RESUMO
A blastomicose sul americana, paracoccidiodomicose (Pb micose) ou doença de Lutz é uma infecção fúngica endêmica na América Latina. É causada pelo fungo dimórfico Paracoccidiodes brasiliensis, e pode causar lesões na mucosa oral. Nós avaliamos a incidência de lesões orais de Pb micose nos pacientes atendidos em um Centro Especializado em Diagnóstico Oral com foco principal nas diferentes formas clinicas das lesões, suas localidades, ocupação dos pacientes, hábitos deletérios e diagnóstico e metodologia, e foram detectados 31 casos (18 pacientes). Os resultados mostraram que 88,8% dos pacientes eram do sexo masculino com idade média de 50 anos de idade, e 39% trabalham, ou trabalhavam, com atividades relacionadas à agricultura. Observou-se que 88,9% eram fumantes e 72,2% ingeriam álcool. Citologia esfoliativa foi feita em 66,6%. Mucosa jugal foi acometida em 30%, gengiva, e lábios 16% (cada um) foram os locais mais comuns de lesões orais da Pb micose. Comparando o diagnóstico inicial com o definitivo feito pelos profissionais, a acurácia foi de 33%; o diagnóstico dos estudantes foi mais preciso demonstrando 72,5% do diagnóstico inicial correto com diferença estatística significante (p=0,25) através do teste ANOVA do SPSS WIN com nível de significância de 5%. Biópsia incisonal e citologia esfoliativa são eficientes para um diagnóstico precoce desta doença na boca; o treinamento dos estudantes em diagnóstico para reconhecer as patologias orais é urgente para melhorar a saúde pública.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Paracoccidioidomycosis / Mouth Diseases Type of study: Diagnostic study / Incidence study / Observational study / Prognostic study / Risk factors / Screening study Limits: Adult / Aged / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Braz. dent. j Journal subject: Dentistry Year: 2012 Type: Article Affiliation country: Brazil Institution/Affiliation country: University of São Paulo/BR

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Index: LILACS (Americas) Main subject: Paracoccidioidomycosis / Mouth Diseases Type of study: Diagnostic study / Incidence study / Observational study / Prognostic study / Risk factors / Screening study Limits: Adult / Aged / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Braz. dent. j Journal subject: Dentistry Year: 2012 Type: Article Affiliation country: Brazil Institution/Affiliation country: University of São Paulo/BR