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Migraine life-time prevalence in mental disorders: concurrent comparisons with first-degree relatives and the general population / Prevalencia de migraña en trastornos mentales: comparación concurrente con familiares de primer grado y con la población general
Baptista, Trino; Uzcátegui, Euderruh; Arapé, Yinet; Serrano, Ana; Mazzarella, Xiorella; Quiroz, Segundo; Ramirez, Clara Isabel; Padrón de Freytez, Alix.
  • Baptista, Trino; Los Andes University. Medical School. Department of Physiology.
  • Uzcátegui, Euderruh; Los Andes University. Medical School. Department of Physiology.
  • Arapé, Yinet; Los Andes University. Medical School. Department of Physiology.
  • Serrano, Ana; Los Andes University. Medical School. Department of Physiology.
  • Mazzarella, Xiorella; Los Andes University. Medical School. Department of Physiology.
  • Quiroz, Segundo; Los Andes University. Medical School. Department of Physiology.
  • Ramirez, Clara Isabel; Los Andes University. Medical School. Department of Physiology.
  • Padrón de Freytez, Alix; Los Andes University. Medical School. Department of Physiology.
Invest. clín ; 53(1): 38-51, mar. 2012. ilus, tab
Article in English | LILACS | ID: lil-664564
ABSTRACT
The authors quantified the prevalence of migraine in subjects with mental disorders, first-degree relatives and the adult general population (GP) in Mérida, Venezuela. After validation, a modified, short version of the Lipton’s diagnostic scale was administered to consecutively admitted in- and out-patients (n = 1059), their first-degree relatives (n = 445) and a probabilistic sample of the GP (n = 516). In the GP, the frequency of migraine (percentage and 95% confidence interval) was 14.9 (11.8-17.9). The migraine frequencies were (percentage and odd ratio probability against the GP bipolar disorder (15.7%, p = 0.5), schizophrenia (8.3%, p = 0.08), depression and dysthimia (24.4%, p = 0.2), anxiety disorders (10.0%, p = 0.02), personality disorders (11.4%, p = 0.15), all other disorders (15.5%, p = 0.4), relatives of bipolar patients (4.4%, p < 0.001), relatives of schizophrenia patients (3.5%, p = 0.003), and relatives of patients with all other mental disorders (12.8%, p = 0.4). Migraine was more common in women (p < 0.001), and the bipolar patients presented the highest female to male ratio (81). A high variability was observed in migraine prevalence among the diagnostic categories, but it was particularly high in subjects with affective disorders, mainly in women, who thus deserve special attention from clinicians.
RESUMEN
Los autores cuantificaron la prevalencia de migraña en sujetos con trastornos mentales, sus familiares de primer grado y la población general (PG) en Mérida, Venezuela. Se utilizó una versión abreviada de la escala diagnostica de Lipton. Luego de un estudio de validez, tal escala se administró a pacientes ambulatorios u hospitalizados atendidos en forma consecutiva (n = 1.059), a sus familiares de primer grado (n = 445) y a una muestra probabilística de la PG (n = 516). La frecuencia de migraña en la PG (porcentaje e intervalo de confianza de 95%) fue de 14,9 (11,8-17,9). La frecuencia para los diversos trastornos (porcentaje y probabilidad asociada a la razón de momios (odds ratio) con respecto a la PG) fue trastorno bipolar (15,7%, p = 0,5), esquizofrenia (8,3%, p = 0,08), depresión y distimia (24,4%, p = 0,2), trastornos de ansiedad (10,0%, p = 0,02), trastornos de personalidad (11,4%, p = 0,15), todos los otros trastornos (15,5%, p = 0,4). En los familiares, la frecuencia fue trastorno bipolar (4,4%, p < 0,001), esquizofrenia (3,5%, p = 0,003), otros trastornos (12,8%, p = 0,4). El diagnóstico de migraña fue más frecuente en mujeres (p < 0,001), y los sujetos con trastorno bipolar presentaron el mayor índice mujerhombre (81). Se observó una alta variabilidad en la prevalencia de migraña en las diversas categorías diagnósticas. Tal frecuencia fue particularmente elevada en sujetos con trastornos afectivos, principalmente en mujeres, las cuales ameritan una atención especial por parte de los médicos tratantes.
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Full text: Available Index: LILACS (Americas) Main subject: Family Health / Mental Disorders / Migraine Disorders Type of study: Controlled clinical trial / Diagnostic study / Prevalence study / Risk factors / Screening study Limits: Adult / Aged / Female / Humans / Male Country/Region as subject: South America / Venezuela Language: English Journal: Invest. clín Journal subject: Biologia / Medicine / Relatos de Casos Year: 2012 Type: Article Affiliation country: Brazil

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Full text: Available Index: LILACS (Americas) Main subject: Family Health / Mental Disorders / Migraine Disorders Type of study: Controlled clinical trial / Diagnostic study / Prevalence study / Risk factors / Screening study Limits: Adult / Aged / Female / Humans / Male Country/Region as subject: South America / Venezuela Language: English Journal: Invest. clín Journal subject: Biologia / Medicine / Relatos de Casos Year: 2012 Type: Article Affiliation country: Brazil