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Perfil clínico-epidemiológico de pacientes con endocarditis infecciosa, período 2003-2010 en el hospital de Temuco, Chile / Profile of patients with infective endocarditis admitted to a Chilean regional hospital
Stockins, Benjamín; Neira, Víctor; Paredes, Alejandro; Castillo, Carlos; Troncoso, Andrés.
  • Stockins, Benjamín; Universidad de La Frontera. Temuco. CL
  • Neira, Víctor; Universidad de La Frontera. Temuco. CL
  • Paredes, Alejandro; Universidad de La Frontera. Temuco. CL
  • Castillo, Carlos; Universidad de La Frontera. Temuco. CL
  • Troncoso, Andrés; Universidad de La Frontera. Temuco. CL
Rev. méd. Chile ; 140(10): 1304-1311, oct. 2012. graf, tab
Article in Spanish | LILACS | ID: lil-668704
ABSTRACT

Background:

Mortality due to infective endocarditis (IE) in Chile is close to 30%.

Aim:

To report the experience with patients admitted with the diagnosis of IE in a regional tertiary hospital. Material and

Methods:

Retrospective study of 107 patients aged 50 ± 16years (75% males) discharged with a definitive diagnosis of IE according to modified DUKE criteria, between years 2003 and 2010. Demographic variables, severity scores, clinical characteristics, bacteriology and hospital evolution were recorded.

Results:

Fifty nine percent of patients had concomitant cardiovascular problems. APACHE II and Sequential Organ Failure Assessment (SOFA) scores on admission were 8.4 ± 4.7 and 2.7 ± 2.8 respectively. Native valves were affected in 91% of cases (aortic and mitral valves in 62% and 50% of cases respectively). Prosthetic valves were affected in 9.3% of cases. Rheumatic heart disease was the predominant primary lesion in 10% of patients. Antibiotics were used in 45.1% before blood cultures were performed. In 68% of patients blood cultures were positive. S. viridans (30.8%), S.aureus (18.6%) and coagulase negative Streptocicci (5.6%) were the identified microorganisms. Intensive care unit admission was required in 48% of patients. Renal, heart and neurological deterioration was observed in 53, 34 and 14% of patients, respectively. Twenty percent of patients developed systemic embolism and 37% required heart surgery. Mean hospital stay was 28.3 ± 19.1 days and 27% of patients died.

Conclusions:

In this series of patients, IE has a high mortality. Most patients studied were admitted in bad conditions.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Streptococcal Infections / Endocarditis, Bacterial / Hospitalization Type of study: Observational study / Prognostic study / Risk factors Limits: Adult / Aged / Female / Humans / Male Country/Region as subject: South America / Chile Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2012 Type: Article Affiliation country: Chile Institution/Affiliation country: Universidad de La Frontera/CL

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Full text: Available Index: LILACS (Americas) Main subject: Streptococcal Infections / Endocarditis, Bacterial / Hospitalization Type of study: Observational study / Prognostic study / Risk factors Limits: Adult / Aged / Female / Humans / Male Country/Region as subject: South America / Chile Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2012 Type: Article Affiliation country: Chile Institution/Affiliation country: Universidad de La Frontera/CL