Perfil clínico-epidemiológico de pacientes con endocarditis infecciosa, período 2003-2010 en el hospital de Temuco, Chile / Profile of patients with infective endocarditis admitted to a Chilean regional hospital
Rev. méd. Chile
;
140(10): 1304-1311, oct. 2012. graf, tab
Article
in Spanish
| LILACS
| ID: lil-668704
ABSTRACT
Background:
Mortality due to infective endocarditis (IE) in Chile is close to 30%.Aim:
To report the experience with patients admitted with the diagnosis of IE in a regional tertiary hospital. Material andMethods:
Retrospective study of 107 patients aged 50 ± 16years (75% males) discharged with a definitive diagnosis of IE according to modified DUKE criteria, between years 2003 and 2010. Demographic variables, severity scores, clinical characteristics, bacteriology and hospital evolution were recorded.Results:
Fifty nine percent of patients had concomitant cardiovascular problems. APACHE II and Sequential Organ Failure Assessment (SOFA) scores on admission were 8.4 ± 4.7 and 2.7 ± 2.8 respectively. Native valves were affected in 91% of cases (aortic and mitral valves in 62% and 50% of cases respectively). Prosthetic valves were affected in 9.3% of cases. Rheumatic heart disease was the predominant primary lesion in 10% of patients. Antibiotics were used in 45.1% before blood cultures were performed. In 68% of patients blood cultures were positive. S. viridans (30.8%), S.aureus (18.6%) and coagulase negative Streptocicci (5.6%) were the identified microorganisms. Intensive care unit admission was required in 48% of patients. Renal, heart and neurological deterioration was observed in 53, 34 and 14% of patients, respectively. Twenty percent of patients developed systemic embolism and 37% required heart surgery. Mean hospital stay was 28.3 ± 19.1 days and 27% of patients died.Conclusions:
In this series of patients, IE has a high mortality. Most patients studied were admitted in bad conditions.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Streptococcal Infections
/
Endocarditis, Bacterial
/
Hospitalization
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Chile
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2012
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Universidad de La Frontera/CL
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