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Venous thromboembolism in Jamaican women: experience in a university hospital in Kingston / Tromboembolismo venoso en mujeres jamaicanas: experiencia en un hospital universitario en Kingston
Fletcher, HM; Wharfe, G; Williams, NP; Pedican, M; Brooks, A; Scott, P; Gordon-Strachan, G.
  • Fletcher, HM; The University of the West Indies. Faculty of Medical Sciences. Departments of Obstetrics and Gynaecology. Kingston. JM
  • Wharfe, G; The University of the West Indies. Faculty of Medical Sciences. Departments of Obstetrics and Gynaecology. Kingston. JM
  • Williams, NP; The University of the West Indies. Faculty of Medical Sciences. Departments of Obstetrics and Gynaecology. Kingston. JM
  • Pedican, M; The University of the West Indies. Faculty of Medical Sciences. Departments of Obstetrics and Gynaecology. Kingston. JM
  • Brooks, A; The University of the West Indies. Faculty of Medical Sciences. Departments of Obstetrics and Gynaecology. Kingston. JM
  • Scott, P; The University of the West Indies. Faculty of Medical Sciences. Departments of Obstetrics and Gynaecology. Kingston. JM
  • Gordon-Strachan, G; The University of the West Indies. Faculty of Medical Sciences. Departments of Obstetrics and Gynaecology. Kingston. JM
West Indian med. j ; 58(3): 243-249, June 2009. tab
Article in English | LILACS | ID: lil-672479
ABSTRACT

OBJECTIVE:

To review cases of venous thromboembolism (VTE) at UHWI from 1999-2004, to identify methods of diagnosis, risk factors and to evaluate differences between survivors and fatalities.

METHODS:

Patients coded with the diagnosis of thromboembolism at the University Hospital of the West Indies (UHWI) from 1999-2004 were identified. The medical records were reviewed to determine the prevalence of thromboembolism and possible variables associated with this diagnosis. In addition, variables associated with fatality were examined by evaluating cases diagnosed at autopsy.

RESULTS:

There were 959 patients coded for thromboembolism between 1999-2004 at UHWI. Of these, 657 (68.5%) were females and 302 were males (31.5%). During that period, 65 657 women and 40 826 men were admitted to hospital with prevalence rates for thromboembolism of 1% in women and 0.7% in men. Of the 657 females, 520 case notes were located (case identification 80%). Of this, 435 were analysed as confirmed thromboembolism. The median age was 51 years with a range of 2-95 years. Common associations were obesity, 53.5%; age over 50 years, 52.5%; hypertension, 44.7%; immobilisation, 36.3%; cardiac disease, 26%; diabetes, 19.4%; fibroids, 16.3%; surgery, 15.8% and cancer 14%. Recurrent venous thromboembolism occurred in 12.8% and 15.8 % of women (66) died, diagnosed with PE at post-mortem. Using logistic regression analysis, leading risk factors in fatalities compared to survivors were hypertension and increased age. Obesity and surgery were significantly more likely in survivors.

CONCLUSION:

Venous thromboembolism was common in this cohort of women and avoidance of risk factors and institution of prophylaxis in high risk women is important to decrease morbidity and mortality.
RESUMEN

OBJETIVO:

Examinar los casos de tromboembolismo venoso (TEV) en el HUWI desde 1999 a 2004, a fin de identificar los métodos de diagnosis y factores de riesgo, y evaluar las diferencias entre sobrevivientes y casos fatales.

MÉTODOS:

Se identificó a los pacientes codificados con el diagnóstico de tromboembolismo en el Hospital Universitario de West Indies (HUWI) de 1999 hasta 2004. Se revisaron las historias clínicas para determinar la prevalencia de tromboembolismo y las variantes posibles asociadas con este diagnóstico. Además, examinamos las variables asociadas con la fatalidad, evaluando los casos diagnosticados mediante autopsia.

RESULTADOS:

Hubo 959 pacientes codificados por tromboembolismo entre 1999-2004 en el HUWI. De estos 657 (68.5%) eran mujeres y 302 eran hombres, 31.5%. Durante ese período, 65 657 mujeres y 40 826 hombres fueron admitidos con tasas de prevalencia de tromboembolismo de 1% en las mujeres y 0.7% en los hombres. De las 657 mujeres, localizamos 520 notas de casos (80% de identificación de casos). De estas, 435 fueron analizadas como tromboembolismos confirmados. La edad promedio fue de 51 años y un rango de 2-95 años. Las asociaciones comunes fueron obesidad (53.5%), edad mayor de 50 años (52.5%), hipertensión (44.7%), inmovilización (36.3%), enfermedad cardíaca (26%), diabetes (19.4%), fibromas (16.3%), cirugía (15.8%), y cáncer (14%). El tromboembolismo venoso recurrente ocurrió en un 12.8%, y murieron 66 (15.8%) mujeres, diagnosticadas post-mortem con EP. Utilizando un análisis de regresión logística, se halló que los principales factores de riesgo en los casos fatales comparados con los de los supervivientes, fueron la hipertensión y los años de edad. La probabilidad de obesidad y cirugía fue significativamente más alta en los sobrevivientes.

CONCLUSIÓN:

El tromboembolismo venoso fue común en esta cohorte de mujeres, y para disminuir la morbilidad y la mortalidad, es importante evitar los factores de riesgo e instituir la profilaxis para las mujeres expuestas a ellos.
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Venous Thromboembolism Type of study: Diagnostic study / Etiology study / Incidence study / Observational study / Prevalence study / Prognostic study / Risk factors Limits: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Male Country/Region as subject: English Caribbean / Jamaica Language: English Journal: West Indian med. j Journal subject: Medicine Year: 2009 Type: Article Affiliation country: Jamaica Institution/Affiliation country: The University of the West Indies/JM

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Full text: Available Index: LILACS (Americas) Main subject: Venous Thromboembolism Type of study: Diagnostic study / Etiology study / Incidence study / Observational study / Prevalence study / Prognostic study / Risk factors Limits: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Male Country/Region as subject: English Caribbean / Jamaica Language: English Journal: West Indian med. j Journal subject: Medicine Year: 2009 Type: Article Affiliation country: Jamaica Institution/Affiliation country: The University of the West Indies/JM