Autismo e epilepsia: modelos e mecanismos / Autism and epilepsy: models and mechanisms
J. epilepsy clin. neurophysiol
;
18(3): 92-96, 2012.
Article
in Portuguese
| LILACS
| ID: lil-673340
RESUMO
O autismo está associado a epilepsia em aproximadamente 30% dos casos com evidências sugerindo a mesma neurofisiopatologia. O mecanismo comum em ambas doenças ainda não está bem definido e a heterogeneidade dos sintomas clínicos nas crianças com transtorno do espectro autista e epilepsia reforça a importância de uma abordagem que inclui a investigação de etiologias biológicas através de estudos de neuroimagem, dos processos inflamatórios, de genética e neuroquímica. Aqui, iremos revisar os principais aspectos da associação entre autismo e epilepsia.
ABSTRACT
Autism is associated with epilepsy in early childhood in almost 30% of children with either disorder, with evidence suggesting the same neurophysiopathology. The common mechanism in both diseases is not well defined and the heterogeneity of clinical symptoms in children with autism spectrum disorder (ASD) and epilepsy highlights the importance of a comprehensive assessment that includes investigation of underlying biological etiologies through neuroimaging, inflammatory, genetic and neurochemistry studies. Here, we review the main aspects of this association between autism and epilepsy.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Autistic Disorder
/
Neurobiology
/
Epilepsy
Limits:
Humans
Language:
Portuguese
Journal:
J. epilepsy clin. neurophysiol
Journal subject:
NEUROCIENCIAS
Year:
2012
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
UNICAMP/BR
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