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Susceptibility to amphotericin B of Candida spp. strains isolated in Ceará, Northeastern Brazil
Silva, Cecília Rocha da; Magalhães, Hemerson Iury Ferreira; Moraes, Manoel Odorico de; Nobre Júnior, Hélio Vitoriano.
  • Silva, Cecília Rocha da; Universidade Federal de Ceará. Faculdade de Farmácia. Departamento de Análises Clinicas e Toxicológicas. Laboratório de Bioprospecção e Experimentação em Leveduras. Fortaleza. BR
  • Magalhães, Hemerson Iury Ferreira; Universidade Federal de Ceará. Faculdade de Farmácia. Departamento de Análises Clinicas e Toxicológicas. Laboratório de Bioprospecção e Experimentação em Leveduras. Fortaleza. BR
  • Moraes, Manoel Odorico de; Universidade Federal de Ceará. Faculdade de Farmácia. Departamento de Análises Clinicas e Toxicológicas. Laboratório de Bioprospecção e Experimentação em Leveduras. Fortaleza. BR
  • Nobre Júnior, Hélio Vitoriano; Universidade Federal de Ceará. Faculdade de Farmácia. Departamento de Análises Clinicas e Toxicológicas. Laboratório de Bioprospecção e Experimentação em Leveduras. Fortaleza. BR
Rev. Soc. Bras. Med. Trop ; 46(2): 244-245, Mar-Apr/2013. tab
Article in English | LILACS | ID: lil-674647
ABSTRACT
Introduction Amphotericin B (AMB) is an antifungal agent used extensively in clinical medicine, yet resistance remains low. This study aims to evaluate the susceptibility of Candida spp. against AMB. Methods For broth microdilution susceptibility testing, 77 strains of Candida spp. were selected (32 C. albicans, 33 C. tropicalis, and 12 C. parapsilosis). The strains were considered susceptible when they exhibited MIC≤1.0µg/ml. Results None of the strains showed an MIC greater than 0.25µg/ml. Conclusions Further works are necessary, with a higher number of strains, to assess the validity of the results used in this study. .
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Full text: Available Index: LILACS (Americas) Main subject: Candida / Amphotericin B / Antifungal Agents Limits: Humans Country/Region as subject: South America / Brazil Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2013 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal de Ceará/BR

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Full text: Available Index: LILACS (Americas) Main subject: Candida / Amphotericin B / Antifungal Agents Limits: Humans Country/Region as subject: South America / Brazil Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2013 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal de Ceará/BR