Idosos hipertensos apresentam menor desempenho cognitivo do que idosos normotensos / Elderly hypertensives show decreased cognitive performance compared with elderly normotensives
Arq. bras. cardiol
;
100(5): 444-451, maio 2013. tab
Article
in Portuguese
| LILACS
| ID: lil-675606
RESUMO
FUNDAMENTO A hipertensão arterial tem sido associada à redução do desempenho cognitivo, contudo a literatura é conflitante. OBJETIVO:
Comparar o desempenho cognitivo entre idosos normotensos ("N"; n = 17; idade 68 ± 1; pressão arterial = 133 ± 3/74 ± 2 mmHg) e hipertensos ("H"; n = 28; idade 69 ± 1, pressão arterial = 148 ± 4/80 ± 1 mmHg) com pelo menos cinco anos de escolaridade.MÉTODOS:
A avaliação neuropsicológica ampla constou do "Cambridge Cognition-Revised" (CAMCOG-R), dos "Trail Making Test A and B" (TMT A e B) e do "Rey Auditory Verbal Learning Test" (RAVLT).RESULTADOS:
Os idosos hipertensos apresentaram menor escore do CAMCOG-R (N = 87,6 ± 1,8; H = 78,6 ± 1,4; p = 0,002). Os idosos hipertensos necessitaram de maior tempo para realizar o TMT A e B (TMT A N = 39 ± 3s; H = 57 ± 3,4s; p = 0,001; TMT B N = 93 ± 7s; H = 124 ± 7s; p = 0,006), o que também é demonstrado pelos percentis significativamente menores obtidos nestes testes. O somatório do RAVLT foi significativamente menor nos idosos hipertensos (N = 51,8 ± 1,7; H = 40,7 ± 1,5; p < 0,0001). Mesmo ajustado para idade, sexo, escolaridade e sintomas de depressão, a hipertensão arterial foi um fator preditor independente do desempenho cognitivo medido pelo CAMCOG-R, TMT A e o somatório do RAVLT.CONCLUSÃO:
O desempenho cognitivo em idosos hipertensos é menor do que em idosos normotensos.ABSTRACT
BACKGROUND:
Essential hypertension has been associated with decreased cognitive performance; however, the literature is conflicting.OBJECTIVE:
This study aims at comparing cognitive performance between elderly normotensives ("N"; n = 17; age 68 ± 1; blood pressure = 133 ± 3/74 ±2 mmHg) and hypertensives ("H"; n = 28; age 69 ± 1, blood pressure = 148 ± 4/80 ± 1mmHg) with at least 5 years of education.METHODS:
The comprehensive neuropsychological assessment was comprised of the Cambridge Cognition-Revised (CAMCOG-R), the Trail Making Test A and B (TMT A and B) and the Rey Auditory Verbal Learning Test (RAVLT).RESULTS:
Elderly hypertensives presented lower CAMCOG-R global scores (N = 87.6 ± 1.8; H = 78.6 ± 1.4; p = 0.002). The hypertensive's performance was slower in the TMT A and B (TMT A N = 39 ± 3s; H = 57 ± 3s; p = 0.001; TMT B N = 93 ± 7s; H = 124 ± 7s; p = 0.006), which was also reflected in smaller percentiles achieved by hypertensives in these tests. Hypertensive subjects exhibited a significantly lower RAVLT summation score (N = 51.8 ± 1.7; H = 40.7 ± 1.5; p < 0.0001). Even when adjusted for age, sex, education and depression symptoms, hypertension was an independent predictor of cognitive performance as measured by CAMCOG-R global score, TMT A and RAVLT summation score.CONCLUSION:
Cognitive performance is lower in elderly hypertensives as compared with elderly normotensives.
Full text:
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Index:
LILACS (Americas)
Main subject:
Blood Pressure
/
Cognition
/
Hypertension
Type of study:
Controlled clinical trial
/
Prognostic study
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
Portuguese
Journal:
Arq. bras. cardiol
Journal subject:
Cardiology
Year:
2013
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade do Estado do Rio de Janeiro/BR
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