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Impact of coronary artery bypass grafting in elderly patients / Impacto da cirurgia de revascularização do miocárdio em pacientes idosos
Aikawa, Priscila; Cintra, Angélica Rossi Sartori; Leite, Cleber Aparecido; Marques, Ricardo Henrique; Silva, Claudio Tafarel Mackmillan da; Afonso, Max dos Santos; Paulitsch, Felipe da Silva; Oss, Evandro Augusto.
  • Aikawa, Priscila; University of Sao Paulo. Faculty of Medicine.
  • Cintra, Angélica Rossi Sartori; University of Sao Paulo. Faculty of Medicine.
  • Leite, Cleber Aparecido; University of Sao Paulo. Faculty of Medicine.
  • Marques, Ricardo Henrique; University of Sao Paulo. Faculty of Medicine.
  • Silva, Claudio Tafarel Mackmillan da; University of Sao Paulo. Faculty of Medicine.
  • Afonso, Max dos Santos; University of Sao Paulo. Faculty of Medicine.
  • Paulitsch, Felipe da Silva; University of Sao Paulo. Faculty of Medicine.
  • Oss, Evandro Augusto; University of Sao Paulo. Faculty of Medicine.
Rev. bras. cir. cardiovasc ; 28(1): 22-28, jan.-mar. 2013. ilus, tab
Article in English | LILACS | ID: lil-675869
ABSTRACT

OBJECTIVE:

To analyze the results of isolated on-pump coronary artery bypass graft surgery (CABG) in patients > 65 years-old.

METHODS:

Patients undergoing isolated on-pump CABG from December 1st 2010 to July 31th 2012 were divided in two groups GE (elderly > 65 years-old, n=103) and GA (adults < 65 years-old, n=150). Preoperative data, intraoperative (as cardiopulmonar bypass time, aortic clamping time, time length of stay in mechanical ventilation - MV - and number of grafts), and postoperative variable (as morbidity, mortality and time length of stay in hospital) were analyzed during hospitalization.

RESULTS:

In GE, the morbidity rate was greater than in GA (30% vs. 14%, P=0.004), but there was no difference in the mortality rate (5.8% vs. 2.0%, P=0.165). In GA, there was higher prevalence DM (39.6% vs. 27%, P=0.043) and smoking (32.2% versus 19.8%, P=0.042); and in GE, higher prevalence of stroke (17% vs. 6.7%, P=0.013). There was no difference between the groups regarding intraoperative variables. After multivariate analysis, age > 65-year-old was associated with greater morbidity, but it was not independent predictive factor for in-hospital mortality. Considering in-hospital mortality, stay in ward time length (P=0.006), cardiac (P=0.011) and respiratory complications (P=0.026) were independent predictive factors.

CONCLUSION:

This study suggests that patients > 65-year old were at increased risk of postoperative complications when submitted to isolated on-pump CABG in comparison to patients < 65-year-old, but not under increased risk of death.
RESUMO

OBJETIVO:

Analisar os desfechos da cirurgia de revascularização do miocárdio (CRM) isolada com circulação extracorpórea em pacientes com idade > 65 anos em comparação àqueles com < 65 anos.

MÉTODOS:

foram analisados 253 pacientes submetidos consecutivamente à CRM isolada entre 1º de dezembro de 2010 a 31 de julho de 2012. Os pacientes foram separados em dois grupos GI (idosos > 65 anos) e GA (adultos < 65 anos). Foram analisadas variáveis pré-operatórias, intraoperatórias (tempo de CEC, tempo de pinçamento aórtico, tempo de submissão à VM e número de enxertos) e pós-operatórias (morbidade, mortalidade e tempo de internação).

RESULTADOS:

Dos 253 pacientes, 103 pertenciam ao GI (40,7%) e 150 ao GA (59,3%). A taxa de morbidade foi significativamente maior no GI quando comparada ao GA (30% vs. 14%, P=0,004), porém não houve diferença na taxa de mortalidade (5,8% vs. 2,0%, P=0,165). No GA havia maior prevalência DM (39,6% vs. 27%, P=0,043) e tabagismo (32,2% vs. 19,8%, P=0,042); e no GI, maior prevalência de acidente vascular encefálico prévio (17% vs. 6,7%, P=0,013). Não houve diferença entre os grupos quanto às variáveis intraoperatórias. Na análise multivariada tempo de internação na enfermaria (P=0,006), complicações cardíacas (P=0,011) e complicações respiratórias (P=0,026) foram variáveis preditoras de risco para maior mortalidade intra-hospitalar. No entanto, a idade > 65 anos não foi um fator preditor de risco associada a variável óbito.

CONCLUSÃO:

Este estudo sugere que pacientes com idade igual ou superior a 65 anos possuem um maior risco de complicações intra-hospitalares no pós-operatório de CRM isolada com CEC em comparação com pacientes mais jovens.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Postoperative Complications / Coronary Artery Bypass Type of study: Prognostic study / Risk factors Limits: Aged / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Rev. bras. cir. cardiovasc Journal subject: Cardiology / General Surgery Year: 2013 Type: Article / Project document Affiliation country: Brazil

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Full text: Available Index: LILACS (Americas) Main subject: Postoperative Complications / Coronary Artery Bypass Type of study: Prognostic study / Risk factors Limits: Aged / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Rev. bras. cir. cardiovasc Journal subject: Cardiology / General Surgery Year: 2013 Type: Article / Project document Affiliation country: Brazil