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Argyria - Case report / Argiria - Relato de caso
Anais Brasileiros de Dermatologia; Lencastre, André; Lobo, Maria; Alexandre João.
  • Lencastre, André; Central Lisbon Hospital Center. Dermatology Service of the Santo António dos Capuchos Hospital. Intern in the Dermatology-Venerology Department. Lisbon. PT
  • Lobo, Maria; Central Lisbon Hospital Center. Dermatology Service of the Santo António dos Capuchos Hospital. Intern in the Dermatology-Venerology Department. Lisbon. PT
  • Alexandre João; Central Lisbon Hospital Center. Dermatology Service of the Santo António dos Capuchos Hospital. Intern in the Dermatology-Venerology Department. Lisbon. PT
An. bras. dermatol ; 88(3): 413-416, jun. 2013. tab, graf
Article in English | LILACS | ID: lil-676223
ABSTRACT
A 70-year-old male rural worker was referred to our clinic with widespread grey pigmentation of the skin and nails. The condition had been asymptomatic for its entire duration (5 years). He reported past intranasal application of 10% Silver Vitellinate. A skin biopsy was performed and histology corroborated the clinical diagnosis of Argyria. This case represents a currently rare dermatological curiosity. Although silver colloids and salts have been withdrawn and/or banned by some drug surveillance agencies, they continue to be freely sold and unregulated as food supplements and as ingredients in alternative medicines, thereby risking the emergence of new cases of silver poisoning.
RESUMO
Um homem de 70 anos, trabalhador rural, foi referenciado à nossa consulta por dermatose assintomática, com 5 anos de evolução, caracterizada pela pigmentação acinzentada generalizada da pele, mais evidente em áreas fotoexpostas, e das lâminas ungueais. Relatava no passado o uso prolongado de Vitelinato de Prata a 10%, por via nasal. Foi efetuado exame histológico de biopsia cutânea que corroborou o diagnóstico clínico de Argiria. O caso representa uma curiosidade dermatológica, atualmente rara. Apesar de abandonados e/ou proibidos por algumas instituições de farmacovigilância, a prata coloidal e sais de prata continuam a ser comercializados como suplementos alimentares, como parte de medicinas alternativas e sem regulação, podendo fazer ressurgir os casos associados à toxicidade pela prata.
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Full text: Available Index: LILACS (Americas) Main subject: Argyria / Skin Type of study: Diagnostic study Limits: Aged / Humans / Male Language: English Journal: An. bras. dermatol Journal subject: Dermatology Year: 2013 Type: Article Affiliation country: Portugal Institution/Affiliation country: Central Lisbon Hospital Center/PT

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Full text: Available Index: LILACS (Americas) Main subject: Argyria / Skin Type of study: Diagnostic study Limits: Aged / Humans / Male Language: English Journal: An. bras. dermatol Journal subject: Dermatology Year: 2013 Type: Article Affiliation country: Portugal Institution/Affiliation country: Central Lisbon Hospital Center/PT