Occult hepatitis B virus infection among injecting drug users in the Central-West Region of Brazil
Mem. Inst. Oswaldo Cruz
;
108(3): 386-389, maio 2013. tab
Article
in English
| LILACS
| ID: lil-676965
ABSTRACT
The prevalence of occult hepatitis B virus (HBV) infection was investigated in 149 hepatitis B surface antigen (HBsAg) negative injecting drug users (IDUs) in the Central-West Region of Brazil. Of these individuals, 19 were positive for HBV DNA, resulting in an occult HBV infection prevalence of 12.7% (19/149); six of these 19 individuals had anti-HBV core and/or anti-HBV surface antibodies and 13 were negative for HBV markers. All IDUs with occult hepatitis B reported sexual and/or parenteral risk behaviours. All HBV DNA-positive samples were successfully genotyped. Genotype D was the most common (17/19), followed by genotype A (2/19). These findings reveal a high prevalence of occult HBV infection and the predominance of genotype D among IDUs in Brazil's Central-West Region.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Hepatitis B virus
/
Drug Users
/
Hepatitis B
/
Hepatitis B Antibodies
/
Hepatitis B Surface Antigens
Type of study:
Diagnostic study
/
Prevalence study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2013
Type:
Article
Affiliation country:
Brazil
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