Your browser doesn't support javascript.
loading
Validity of the International HIV Dementia Scale in Brazil / Validade da Escala Internacional de Demência pelo HIV no Brasil
Arquivos de Neuro-Psiquiatria; Rodrigues, Roiza Almeida; Oliveira, Raquel Lisboa; Grinsztejn, Beatriz; Silva, Marcus Tulius T..
  • Rodrigues, Roiza Almeida; Fundação Oswaldo Cruz (FIOCRUZ). Clinical Research Laboratory on Neuroinfection Diseases, Evandro Chagas Clinical Research Institute (IPEC). MD, MSc, Neurologist. BR
  • Oliveira, Raquel Lisboa; Fundação Oswaldo Cruz (FIOCRUZ). Clinical Research Laboratory on Neuroinfection Diseases, Evandro Chagas Clinical Research Institute (IPEC). MD, MSc, Neurologist. BR
  • Grinsztejn, Beatriz; Fundação Oswaldo Cruz (FIOCRUZ). Clinical Research Laboratory on Neuroinfection Diseases, Evandro Chagas Clinical Research Institute (IPEC). MD, MSc, Neurologist. BR
  • Silva, Marcus Tulius T.; Fundação Oswaldo Cruz (FIOCRUZ). Clinical Research Laboratory on Neuroinfection Diseases, Evandro Chagas Clinical Research Institute (IPEC). MD, MSc, Neurologist. BR
Arq. neuropsiquiatr ; 71(6): 376-379, jun. 2013. tab, graf
Article in English | LILACS | ID: lil-677602
ABSTRACT

id="para1">HIV-associated neurocognitive disorders (HAND) remain prevalent in highly active antiretroviral therapy (HAART) era. Tests to detect HAND are needed for early diagnosis and treatment. Validity of International HIV Dementia Scale (IHDS) has been determined in different countries. The aims of this study were validate IHDS in a Brazilian cohort of HIV-patients and verify if IHDS can be reliably administered by a non-clinician health professional. One hundred and eighty-seven (187) patients were submitted to a full neuropsychological assessment. IHDS was administered twice to each patient (by a non-clinician and by a neurologist). HAND was diagnosed in 98 individuals (68 on HAART). IHDS had sensitivity of 55% and specificity of 80%. IHDS had fair agreement with neuropsychological tests (k 0.355) and moderate-to-strong agreement between different evaluators (interclass correlation coefficient (ICC) 0.684). HAND is prevalent nowadays. IHDS is quick and easy to administer, but has marginal sensitivity for the detection of HIV cognitive impairment other than dementia.

.
RESUMO

id="para2">Distúrbios neurocognitivos associados ao HIV (HAND) ainda são comuns em pacientes usando terapia antirretroviral de alta eficácia (HAART). Testes diagnósticos para detecção de HAND são necessários para diagnóstico e terapia precoces. Nossos objetivos foram validar em uma população brasileira a escala internacional de demência pelo HIV (IHDS), já utilizada em outros países, e avaliar se pode ser confiavelmente aplicada por um profissional não médico. Avaliamos 187 pacientes com uma extensa bateria neuropsicológica. IHDS foi ministrada duas vezes (por médico e não médico). HAND foi diagnosticada em 98 indivíduos (68 em uso de HAART). A IHDS teve sensibilidade de 55% e especificidade de 80%, com pouca concordância com os testes neuropsicológicos (k 0,355) e moderada a forte concordância entre observadores (coeficiente de correlação interclasse (ICC) 0,684). HAND ainda é prevalente nos dias atuais. IHDS é um instrumento rápido e fácil de ser aplicado, mas com baixa sensibilidade para detecção de déficit cognitivo outro que não demência.

.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: AIDS Dementia Complex / Cognition Disorders / Neuropsychological Tests Type of study: Prognostic study / Screening study Limits: Adult / Aged / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Arq. neuropsiquiatr Journal subject: Neurology / Psychiatry Year: 2013 Type: Article Affiliation country: Brazil Institution/Affiliation country: Fundação Oswaldo Cruz (FIOCRUZ)/BR

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Index: LILACS (Americas) Main subject: AIDS Dementia Complex / Cognition Disorders / Neuropsychological Tests Type of study: Prognostic study / Screening study Limits: Adult / Aged / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Arq. neuropsiquiatr Journal subject: Neurology / Psychiatry Year: 2013 Type: Article Affiliation country: Brazil Institution/Affiliation country: Fundação Oswaldo Cruz (FIOCRUZ)/BR