Evaluation of immunohistochemical expression of ghrelin-producing rectal cells in Wistar rats underwent to the cafeteria diet
Acta cir. bras
;
28(8): 614-618, Aug. 2013. ilus, tab
Article
in English
| LILACS
| ID: lil-680617
ABSTRACT
PURPOSE:
To investigate the impact of cafeteria diet on ghrelin expression in rectal tissue and identify the morphologic cell type.METHODS:
Twenty-four male Wistar rats were divided into four subgroups of six animals each RC1 (rat chow 1) and CAF1 (cafeteria diet 1) for a period of 30 days; RC2 (rat chow 2) and CAF2 (cafeteria diet 2) for a period of 60 days. The animal and rectal weight, the number and the type of immunoreactive ghrelin cells were recorded and compared between the subgroups. The statistical study was established by ANOVA and Student's t test.RESULTS:
There was no difference in the total of immunoreactive cells (p=0.685) between the subgroups nor between weight and presence or absence of ghrelin expression (p=0.993). All the immunoreactive cells identified were closed-type.CONCLUSION:
The cafeteria diet did not have influence on the amount of immunoreactive rectal cells of ghrelin and only one type (closed-type) of immunoreactive cells was expressed in the rectum.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Rectum
/
Dietary Carbohydrates
/
Diet
/
Ghrelin
Type of study:
Evaluation studies
/
Prognostic study
Limits:
Animals
Language:
English
Journal:
Acta cir. bras
Journal subject:
General Surgery
/
Procedimentos Cir£rgicos Operat¢rios
Year:
2013
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
UFSC/BR
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