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Clinical characteristics and outcomes of patients admitted with presumed microbial keratitis to a tertiary medical center in Israel / Características clínicas e desfechos dos pacientes internados com diagnóstico de ceratite microbiana em um centro terciário em Israel
Lavinsky, Fabio; Avni-Zauberman, Noah; Barequet, Irina S.
  • Lavinsky, Fabio; Tel Aviv University Sackler. Faculty of Medicine. Sheba Medical Center. Goldschleger Eye Institute. Tel Hashomer. IL
  • Avni-Zauberman, Noah; Tel Aviv University Sackler. Faculty of Medicine. Sheba Medical Center. Goldschleger Eye Institute. Tel Hashomer. IL
  • Barequet, Irina S; Tel Aviv University Sackler. Faculty of Medicine. Sheba Medical Center. Goldschleger Eye Institute. Tel Hashomer. IL
Arq. bras. oftalmol ; 76(3): 175-179, maio-jun. 2013. ilus, tab
Article in English | LILACS | ID: lil-681851
ABSTRACT

PURPOSES:

Microbial keratitis is commonly diagnosed worldwide, and continues to cause significant ocular morbidity, requiring prompt and appropriate treatment. The objective of this study is to describe the clinical characteristics and outcomes of patients with presumed microbial keratitis admitted to The Goldschleger Eye Institute, Sheba Medical Center, Tel Aviv University, Tel Hashomer, Israel.

METHODS:

A cross-sectional study was conducted, in which the medical records of patients with presumed microbial keratitis admitted during a period of 3 years were reviewed.

RESULTS:

Keratitis was diagnosed in 276 patients (51% males and 48.9% females). The mean age was 39.29 ± 22.30 years. The hospital length of stay ranged from 1 to 65 days (mean 5.69 ± 5.508). Fortified antibiotics were still used at discharge in 72% of the cases. Overall visual acuity improved significantly from the time of admission to the 1st-week follow up visit showing a p<0.001 on the Wilcoxon signed ranks test. Contact lens wearing was present in 36.1% of the patients, although there was no significant relation with severity of the presentation and visual outcome (p>0.05). The degree of hypopyon and cells in the anterior chamber was significantly related to the hospital length of stay (r Spearman=0.31; p<0.001 and r Spearman=0.21; p<.001, respectively) as well as to a worse visual outcome (r Spearman=0.32; p<0.01 and r Spearman=0.18; p=0.01, respectively). Of all patients, 2.3% required an urgent therapeutic penetrating keratoplasty, and 1% underwent evisceration. There was no enucleation.

CONCLUSION:

Treating keratitis aggressively and assuring patient compliance is imperative for a good final visual outcome. Inpatient treatment may have a positive impact on this outcome.
RESUMO

OBJETIVOS:

Ceratite microbiana é comumente diagnosticada em todo mundo e ainda continua a causar uma significante morbidade ocular. É necessário tratá-la de forma imediata e apropriada. O objetivo deste estudo é descrever as características clínicas e os desfechos dos pacientes com ceratite microbiana presumida que foram internados no Goldschlager Eye Institute, Sheba Medical Center, Tel Aviv University, Israel.

MÉTODOS:

Um estudo transversal foi realizado onde arquivos hospitalares dos pacientes internados com ceratite microbiana presumida durante um periodo de três anos foram analisados e revisados.

RESULTADOS:

Ceratite foi diagnosticada em 276 pacientes (51% masculinos e 48,9% femininos). A média de idade foi 39,29 ± 22,30 anos. A duração da internação foi de 1 a 65 dias (média 5,69 ± 5,508). Antibióticos fortificados permaneceram usados na alta em 72% dos casos. A acuidade visual do seguimento da primeira semana após a alta em relação a internação melhorou na media de forma estatisticamente significativa (p<0,001 usando Wilcoxon signed ranks test). O uso de lentes de contato estava presente em 36,1% dos pacientes, porém não houve relação estatisticamente significativa entre a gravidade da apresentação clínica e a acuidade visual nestes pacientes (p>0,05). O grau de hipópio e células na câmara anterior foram estatisticamente significativos em relação ao tempo de internação (r Spearman=0,0.31; p<0,001 and r Spearman=0,21; p<0,001, respectivamente) e para a acuidade visual (r Spearman=0,32; p<0,01 e r Spearman=0,18; p=0,01, respectivamente). De todos os pacientes, apenas 2,3% necessitaram ceratoplastia penetrante urgente e 1% necessitaram evisceração. Não houve enucleações.

CONCLUSÕES:

Tratar a ceratite de forma agressiva e garantir a aderência do paciente ao tratamento é imperativo para o bom resultado visual final. O tratamento internado pode ter um impacto positivo neste desfecho.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Keratitis Type of study: Diagnostic study / Observational study / Prevalence study / Prognostic study / Risk factors Limits: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: Asia Language: English Journal: Arq. bras. oftalmol Journal subject: Ophthalmology Year: 2013 Type: Article Affiliation country: Israel Institution/Affiliation country: Tel Aviv University Sackler/IL

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Full text: Available Index: LILACS (Americas) Main subject: Keratitis Type of study: Diagnostic study / Observational study / Prevalence study / Prognostic study / Risk factors Limits: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: Asia Language: English Journal: Arq. bras. oftalmol Journal subject: Ophthalmology Year: 2013 Type: Article Affiliation country: Israel Institution/Affiliation country: Tel Aviv University Sackler/IL