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Diffusion-weighted magnetic resonance imaging: biomarker for treatment response in oncology / Ressonância magnética com difusão: biomarcador de resposta terapêutica em oncologia
Radiologia Brasileira; Testa, Maria Luiza; Chojniak, Rubens; Sene, Leticia Silva; Damascena, Aline Santos.
  • Testa, Maria Luiza; Hospital A. C. Camargo. Sao Paulo. BR
  • Chojniak, Rubens; Hospital A. C. Camargo. Sao Paulo. BR
  • Sene, Leticia Silva; Hospital A. C. Camargo. Sao Paulo. BR
  • Damascena, Aline Santos; Hospital A. C. Camargo. Sao Paulo. BR
Radiol. bras ; 46(3): 178-180, May-Jun/2013. graf
Article in English | LILACS | ID: lil-681925
ABSTRACT
The authors report a case where a quantitative assessment of the apparent diffusion coefficient (ADC) of liver metastasis in a patient undergoing chemotherapy has shown to be an effective early marker for predicting therapeutic response, anticipating changes in tumor size. A lesion with lower initial ADC value and early increase in such value in the course of the treatment tends to present a better therapeutic response.
RESUMO
Relatamos um caso no qual a avaliação quantitativa do coeficiente de difusão aparente (ADC) de metástases hepáticas submetidas a quimioterapia se mostrou um bom preditor e marcador precoce de resposta terapêutica, antecipando alterações de tamanho. Lesão com valor inicial do ADC mais baixo e com aumento precoce deste valor no curso do tratamento tende a apresentar melhor resposta terapêutica tardia.


Full text: Available Index: LILACS (Americas) Language: English Journal: Radiol. bras Journal subject: Diagnostic Imaging / Radiology Year: 2013 Type: Article Affiliation country: Brazil Institution/Affiliation country: Hospital A. C. Camargo/BR

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Full text: Available Index: LILACS (Americas) Language: English Journal: Radiol. bras Journal subject: Diagnostic Imaging / Radiology Year: 2013 Type: Article Affiliation country: Brazil Institution/Affiliation country: Hospital A. C. Camargo/BR