Effects of Dangguibuxue Tang, a Chinese herbal medicine, on growth performance and immune responses in broiler chicks
Biol. Res
;
46(2): 183-188, 2013. graf, tab
Article
in English
| LILACS
| ID: lil-683996
ABSTRACT
The effects of Dangguibuxue Tang (DBT) on growth performance and immunity response in immunosuppressed broiler chicks were investigated in this study. 240 one-d-old broiler chicks (DaHeng S01) were randomly divided into 4 groups, 2.0% DBT-treatment (A), 0.5% DBT-treatment (B), cyclophosphamide-control (C), and control group (D). From 4 d to 7 d of age, chicks in group A, B and C were given cyclophosphamide (CY) at a dosage of 100mg/kg body weight (BW) daily by intraperitoneal injection to induce immunosuppression. Chicks in group D were given an equal volume of physiological saline daily by intraperitoneal injection and considered normal chicks. Groups A and B were supplemented with 2.0% or 0.5% of DBT in the drinking water from 8 d to 42 d of age. Groups C and D did not receive any additional medication. The results revealed that chicks from group B had lower feedgain rate (FGR), lower total mortality, higher immunity organ indexes, higher levels of Newcastle disease (ND) antibody and infectious bursal disease (IBD) antibody, higher interleukin-2 and interleukin-6 levels, and greater lymphocyte proliferative responses to concanavalin A (ConA) during the experiment than those from group C. However, no significant difference in the immunity status in the two levels of DBT-treatment was observed. These results indicate that supplementation of 0.5% of DBT can improve both cellular immunity and humoral immunity in immunosuppressed broiler chicks.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Drugs, Chinese Herbal
/
Chickens
/
Birnaviridae Infections
/
Infectious bursal disease virus
/
Newcastle Disease
Limits:
Animals
Language:
English
Journal:
Biol. Res
Journal subject:
Biology
Year:
2013
Type:
Article
/
Project document
Affiliation country:
China
Institution/Affiliation country:
Sichuan Animal Science Academy/CN
Similar
MEDLINE
...
LILACS
LIS