Autonomic evaluation of hepatitis C virus infected patients / Avaliacao autonomica de pacientes infectados pelo virus da hepatite C
Arq. neuropsiquiatr
;
71(8): 537-539, ago. 2013. tab, graf
Article
in English
| LILACS
| ID: lil-684087
ABSTRACT
There are few studies reporting the association between hepatitis C virus (HCV) infection and disautonomia. We have evaluated the autonomic cardiovascular function in 12 patients with sensory small-fiber polyneuropathy infected by HCV. The mean age was 49±13 years old. The mean infection time was 9.6 years in six (50%) patients. Thermal and pinprick hypoesthesia was observed in distal legs in all patients. Autonomic symptoms were referred by eight (66.7%) patients. Among patients with abnormal autonomic cardiovascular test, five (41.7%) showed abnormal results in two or more tests. Valsalva maneuver was abnormal in seven (58.3%) patients. We can consider that there is an association of both parasympathetic and sympathetic efferent cardiovascular dysfunction in this group of patients.
RESUMO
Existem poucos estudos que relatam a associação entre infecção pelo vírus da hepatite C (HCV) e disautonomia. Avaliamos a função autonômica cardiovascular em 12 pacientes com polineuropatia de fibras finas e infectados pelo HCV. A idade média foi de 49±13 anos. O tempo de infecção média foi de 9,6 anos em seis (50%) pacientes. Hipoestesia termoalgésica foi observada nos segmentos distais das pernas em todos os pacientes. Sintomas autonômicos foram relatados por oito (66,7%) pacientes. No teste autonômico cardiovascular, cinco (41,7%) apresentaram resultados anormais em dois ou mais testes. Manobra de Valsalva foi anormal em sete (58,3%) pacientes. Podemos considerar que há comprometimento de ambas as vias parassimpática e simpática cardiovasculares eferentes nesse grupo de pacientes.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Autonomic Nervous System
/
Cardiovascular System
/
Hepatitis C
/
Primary Dysautonomias
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Arq. neuropsiquiatr
Journal subject:
Neurology
/
Psychiatry
Year:
2013
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
UPC/BR
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