Ponderal behavior of rats fed an omegas 3, 6 and 9 enriched diet submitted to colon carcinogenesis induced by azoxymethane
Acta cir. bras
;
28(10): 721-727, Oct. 2013. ilus, tab
Article
in English
| LILACS
| ID: lil-687746
ABSTRACT
PURPOSE:
To assess weight changes in rats fed diets with different ratios of omegas 3, 6 and 9 submitted to colonic carcinogenesis induced by Azoxymethane (AOM).METHODS:
Sixty rats with three weeks of life were distributed into five groups of specific diets containing 12 animals each GI- Standard diet without adminstration of AOM, GII- Standard diet with adminstration of AOM; GIII- Hyperlipidic diet with adminstration of AOM; GIV-Normolipidic diet with adminstration of AOM; GV- Hypolipidic diet with adminstration of AOM. The weight and food intake of each group were assessed four times in each week throughout the experiment until euthanasia at 36th week.RESULTS:
GI and GII had no significant difference in weight. GI showed a significant increase when compared to GIII, GIV and GV. GII also showed a significant increase when compared to GIII, GIV and GV. When comparing intake of GI as compared to GII no significant difference was found, however such groups had higher intake than groups III, IV and V. There were found no difference in weight when comparing amoung rats with and without cancer within each groups GII, GIII, GIV and GV.CONCLUSIONS:
Diets rich in omega 3, 6 and 9 reduced food intake and weight. Rats with colorectal cancer had no decrease in weight as compared to those without this condition in the same group.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Body Weight
/
Food, Fortified
/
Colonic Neoplasms
/
Eating
/
Fatty Acids, Unsaturated
Limits:
Animals
Language:
English
Journal:
Acta cir. bras
Journal subject:
General Surgery
/
Procedimentos Cir£rgicos Operat¢rios
Year:
2013
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Federal University of Ceara/BR
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