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Psoriasis: correlation between severity index (PASI) and systemic treatment / Psoriase: correlacao entre gravidade clinica (PASI) e qualidade de vida (DLQI) em pacientes avaliados antes e depois de tratamento sistemico
Silva, Maria Flavia Pereira da; Fortes, Maria Rita Parise; Miot, Luciane Donida Bartoli; Marques, Silvio Alencar.
  • Silva, Maria Flavia Pereira da; Marilia University. Department of Pathology. Marilia. BR
  • Fortes, Maria Rita Parise; Marilia University. Department of Pathology. Marilia. BR
  • Miot, Luciane Donida Bartoli; Marilia University. Department of Pathology. Marilia. BR
  • Marques, Silvio Alencar; Marilia University. Department of Pathology. Marilia. BR
An. bras. dermatol ; 88(5): 760-763, out. 2013. tab
Article in English | LILACS | ID: lil-689710
ABSTRACT

BACKGROUND:

Psoriasis is a chronic inflammatory disease of the skin that affects patients of all ages andboth genders. The impact of the disease on quality of life is greater among patients with moderate to severe psoriasis.

OBJECTIVE:

to establish a correlation between the psoriasis area and severity index (PASI) and theDermatology Life Quality Index (DLQI) based on a quality of life questionnaire adapted to the Brazilian contextfor patients with plaque psoriasis before and after systemic treatment.

METHODS:

This was a cross-sectional, descriptive study of psoriasis patients who did not undergo treatment or who manifested clinical activity of the disease. Patients were evaluated according to the PASI and the quality of life questionnaire adapted to theBrazilian context before and 60 days after systemic treatment.

RESULTS:

Thirty-five patients participated in thestudy. Twenty-six were men, with a mean age of 46 years. There was no correlation between the PASI and thequality of life questionnaire adapted to the Brazilian context, but there was a correlation between the PASI andsome items of the quality of life questionnaire adapted to the Brazilian context, such as jobs involving public contact.

CONCLUSION:

The non-correlation between the PASI and the quality of life questionnaire adapted to the Brazilian context in this work may be associated with a history of chronic disease, which implies greater acceptance of the illness, or may be related to the low income and social status of the patients studied. The correlationobserved among patients with careers involving public contact suggests that some professions are more impacted by the disease. It may be necessary to adapt the quality of life questionnaire to patients with a low income andcultural and social limitations. The small sample size (n=35 patients) and the short follow-up period of 60 dayswere some of the limitations of this work. .
RESUMO
FUNDAMENTOS Psoríase é doença inflamatória crônica da pele que afeta pacientes de todas as idades eambos os gêneros. O impacto negativo na qualidade de vida é mais importante naqueles pacientes com psoríasemoderada a grave.

OBJETIVO:

Correlacionar o índice de gravidade e extensão da psoríase e o índice de qualidadede vida, segundo questionário de qualidade de vida adaptado ao Brasil, em pacientes de psoríase em placas antes e depois de tratamento sistêmico.

MÉTODO:

Estudo transversal, descritivo, de pacientes de psoríase, virgens detratamento ou em atividade clinica, submetidos a avaliação do índice de gravidade e extensão da psoríase e aoquestionário de qualidade de vida adaptado ao Brasil antes e após 60 dias de tratamento com medicação sistêmica.

RESULTADOS:

Trinta e cinco pacientes foram estudados, 26 homens, com idade média de 46 anos. Não houvecorrelação entre índice de gravidade e extensão da psoríase e questionário de qualidade de vida adaptado aoBrasil. Mas, houve correlação entre índice de gravidade e extensão da psoríase e itens do questionário de qualidade de vida adaptado ao Brasil, tal como "atividade profissional com público".

CONCLUSÃO:

A não correlação entre índice de gravidade e extensão da psoríase e questionário de qualidade de vida adaptado ao Brasil nessainvestigação pode estar relacionada com história crônica de psoríase, o que implicaria em melhor aceitação dadoença ao longo do tempo ou às condições sociais e de baixa renda dos pacientes estudados. A correlação observada entre aqueles com atividade pública sugere que algumas profissões podem sofrer maior impacto da enfermidade. ...
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Psoriasis / Quality of Life / Severity of Illness Index Type of study: Observational study / Prevalence study / Risk factors Limits: Adult / Aged / Aged80 / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: An. bras. dermatol Journal subject: Dermatology Year: 2013 Type: Article Affiliation country: Brazil Institution/Affiliation country: Marilia University/BR

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Full text: Available Index: LILACS (Americas) Main subject: Psoriasis / Quality of Life / Severity of Illness Index Type of study: Observational study / Prevalence study / Risk factors Limits: Adult / Aged / Aged80 / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: An. bras. dermatol Journal subject: Dermatology Year: 2013 Type: Article Affiliation country: Brazil Institution/Affiliation country: Marilia University/BR