Modulation of cerebral malaria by curcumin as an adjunctive therapy
Braz. j. infect. dis
;
17(5): 579-591, Sept.-Oct. 2013. ilus, tab
Article
in English
| LILACS
| ID: lil-689884
ABSTRACT
Cerebral malaria is the most severe and rapidly fatal neurological complication of Plasmodium falciparum infection and responsible for more than two million deaths annually. The current therapy is inadequate in terms of reducing mortality or post-treatment symptoms such as neurological and cognitive deficits. The pathophysiology of cerebral malaria is quite complex and offers a variety of targets which remain to be exploited for better therapeutic outcome. The present review discusses on the pathophysiology of cerebral malaria with particular emphasis on scope and promises of curcumin as an adjunctive therapy to improve survival and overcome neurological deficits.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Adjuvants, Pharmaceutic
/
Malaria, Cerebral
/
Curcumin
/
Antimalarials
Limits:
Humans
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2013
Type:
Article
Affiliation country:
India
Institution/Affiliation country:
J.S.S. College of Pharmacy/IN
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